Correlation Catalog M. tuberculosis H37Rv: Rv2868c - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase gcpE

Click on the question marks for explanations Hide help
Distribution of gene correlation: Rv2868c vs. all genes ?
COG Categories ?

Information storage and processing

J Translation, ribosomal structure and biogenesis

K Transcription

I DNA replication, recombination and repair

Cellular Processes

D Cell division and chromosome partitioning

O Posttranslational modification, protein turnover, chaperones

M Cell envelope biogenesis, outer membrane

N Cell motility and secretion

P Inorganic transport and metabolism

T Signal transduction mechanisms

Metabolism

C Energy production and conversion

G Carbohydrate transport and metabolism

E Amino acid transport and metabolism

F Nucleotide transport and metabolism

H Coenzyme metabolism

I Lipid metabolism

Q Secondary metabolites biosynthesis, transport and catabolism

Poorly characterized

R General function predicton only

S Unknown function

X No COG assigned

Genes with negative correlation ?

 Categories Enriched ?: L

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv2716 conserved hypothetical protein   -0.49457
Rv1031 potassium-transporting ATPase C chain kdpC   -0.45657
Rv1926c immunogenic protein mpt63   -0.41362
Rv3521 conserved hypothetical protein   -0.41141
Rv1270c lipoprotein lprA   -0.40735
Rv0008c membrane protein   -0.40102
Rv2269c hypothetical protein   -0.39955
Rv1170 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase mshB   -0.39922
Rv1141c enoyl-CoA hydratase echA11   -0.39675
Rv2713 soluble pyridine nucleotide transhydrogenase sthA   -0.39664
Rv1499 hypothetical protein   -0.39619
Rv3651 conserved hypothetical protein   -0.39531
Rv3108 hypothetical protein   -0.39194
Rv2807 conserved hypothetical protein   -0.38774
Rv1764 transposase   -0.38062
Rv0305c PPE family protein   -0.37563
Rv2253 secreted protein   -0.37506
Rv2019 hypothetical protein   -0.37433
Rv3714c conserved hypothetical protein   -0.37428
Rv0277c conserved hypothetical protein   -0.37241
Rv3109 molybdenum cofactor biosynthesis protein A moaA1   -0.37128
Rv1137c hypothetical protein   -0.36899
Rv0891c transcriptional regulator   -0.36621
Rv3333c hypothetical proline rich protein   -0.36382
Rv2167c transposase   -0.36232
Rv0523c conserved hypothetical protein   -0.36122
Rv2336 hypothetical protein   -0.36062
Rv3143 response regulator   -0.36002
Rv0304c PPE family protein   -0.35879
Rv3788 hypothetical protein   -0.35871
Rv2633c hypothetical protein   -0.35833
Rv3187 transposase   -0.35701
Rv3789 conserved membrane protein   -0.35667
Rv3787c conserved hypothetical protein   -0.3566
Rv0256c PPE family protein   -0.35579
Rv2282c transcriptional regulator, lysR-family   -0.35497
Rv3475 transposase   -0.35437
Rv1469 cation transporter P-type ATPase D ctpD   -0.35321
Rv3669 conserved membrane protein   -0.35242
Rv3359 oxidoreductase   -0.35214
Rv1903 conserved membrane protein   -0.35109
Rv1365c anti-anti-sigma factor rsfA   -0.35073
Rv1369c transposase   -0.34812
Rv0645c methoxy mycolic acid synthase 1 mmaA1   -0.34683
Rv1777 cytochrome P450 144 cyp144   -0.34546
Rv3379c 1-deoxy-D-xylulose 5-phosphate synthase dxs2   -0.34457
Rv3488 conserved hypothetical protein   -0.34445
Rv0397 13E12 repeat family protein   -0.34252
Rv0741 transposase   -0.34219
Rv3185 transposase   -0.34087
Rv0601c two component system sensor kinase   -0.34027
Rv2021c transcriptional regulator   -0.33994
Rv0739 conserved hypothetical protein   -0.33961
Rv1490 membrane protein   -0.33859
Rv0355c PPE family protein   -0.33737
Rv0573c conserved hypothetical protein   -0.33579
Rv3912 hypothetical alanine rich protein   -0.33539
Rv1517 conserved membrane protein   -0.33525
Rv2355 transposase   -0.33517
Rv0759c conserved hypothetical protein   -0.33507
Rv2177c transposase   -0.33418
Rv2129c oxidoreductase   -0.33396
Rv0895 conserved hypothetical protein   -0.33373
Rv1978 conserved hypothetical protein   -0.32995
Rv1581c phiRv1 phage protein   -0.32709
Rv2479c transposase   -0.32692
Rv1549 fatty-acid-CoA ligase fadD11_1   -0.32669
Rv0363c fructose-bisphosphate aldolase fba   -0.32465
Rv1538c L-aparaginase ansA   -0.32406
Rv0796 transposase   -0.32399
Rv1756c transposase   -0.32397
Rv3845 hypothetical protein   -0.32295
Rv1204c conserved hypothetical protein   -0.32253
Rv2601 spermidine synthase speE   -0.32242
Rv3082c araC/xylS-family virulence-regulating transcriptional regulator virS   -0.32177
Rv1039c PPE family protein   -0.31896
Rv0943c monooxygenase   -0.3185
Rv0893c conserved hypothetical protein   -0.31806
Rv1891 conserved hypothetical protein   -0.31782
Rv1988 methyltransferase   -0.31759
Rv2295 conserved hypothetical protein   -0.31752
Rv0090 membrane protein   -0.31651
Rv1984c cutinase precursor cfp21   -0.31587
Rv3820c polyketide synthase associated protein papA2   -0.31496
Rv0375c carbon monoxyde dehydrogenase medium chain   -0.31493
Rv1675c transcriptional regulator   -0.31467
Rv2273 conserved membrane protein   -0.31347
Rv2023c hypothetical protein   -0.31315
Rv3831 hypothetical protein   -0.3121
Rv3349c transposase   -0.31012
Rv2106 transposase   -0.30924
Rv2059 conserved hypothetical protein   -0.30889
Rv2999 lipoprotein lppY   -0.30869
Rv1815 conserved hypothetical protein   -0.3083
Rv1489c   -0.30821
Rv0117 oxidative stress response regulatory protein oxyS   -0.30753
Rv3112 molybdenum cofactor biosynthesis protein D moaD1   -0.30694
Rv3098c hypothetical protein   -0.30563
Rv3347c PPE family protein   -0.30562
Rv2607 pyridoxamine 5-phosphate oxidase pdxH   -0.3045
Rv0130 conserved hypothetical protein   -0.30437
Rv0347 conserved membrane protein   -0.30409
Rv3130c conserved hypothetical protein   -0.30397
Rv2142c hypothetical protein   -0.3034
Rv0259c conserved hypothetical protein   -0.30184
Rv0032 8-amino-7-oxononanoate synthase bioF2   -0.30059

Genes with positive correlation ?

 Categories Enriched ?: N O

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv3626c conserved hypothetical protein   0.5738
Rv2444c ribonuclease E rne   0.54629
Rv3240c preprotein translocase secA1   0.54531
Rv3610c membrane-bound ell division protein ftsH   0.51787
Rv1410c aminoglycosides/tetracycline-transport membrane protein   0.51155
Rv1294 homoserine dehydrogenase thrA   0.51076
Rv1596 nicotinate-nucleotide pyrophosphatase nadC   0.50305
Rv0724 protease IV sppA   0.49921
Rv3596c ATP-dependent protease ATP-binding subunit clpC1   0.49396
Rv3244c lipoprotein lpqB   0.4939
Rv3802c conserved membrane protein   0.48219
Rv2097c conserved hypothetical protein   0.47762
Rv0018c serine/threonine phosphatase ppp   0.47643
Rv1925 acyl-CoA ligase fadD31   0.47534
Rv2109c proteasome alpha subunit prcA   0.47306
Rv1072 conserved membrane protein   0.47267
Rv2454c oxidoreductase beta subunit   0.47181
Rv3212 conserved alanine and valine rich protein   0.47084
Rv3256c conserved hypothetical protein   0.46625
Rv1300 hypothetical protein hemK   0.46555
Rv3876 conserved alanine and proline rich protein   0.46116
Rv1700 conserved hypothetical protein   0.46087
Rv2460c ATP-dependent clp protease proteolytic subunit 2 clpP2   0.46047
Rv0049 conserved hypothetical protein   0.45224
Rv0530 conserved hypothetical protein   0.45211
Rv2586c protein-export membrane protein secF   0.45122
Rv3608c dihydropteroate synthase 1 folp   0.44893
Rv3868 conserved hypothetical protein   0.44744
Rv0005 DNA gyrase subunit B gyrB   0.44621
Rv3870 conserved membrane protein   0.44424
Rv2869c conserved membrane protein   0.44336
Rv2942 transmembrane transport protein mmpL7   0.44315
Rv1836c conserved hypothetical protein   0.44269
Rv3682 bifunctional membrane-associated penicillin-binding protein 1A/1B ponA2   0.44236
Rv1843c inosine-5-monophosphate dehydrogenase guaB1   0.44123
Rv3609c GTP cyclohydrolase I folE   0.44006
Rv1466 conserved hypothetical protein   0.43984
Rv2210c branched-chain amino acid transaminase ilvE   0.43957
Rv0486 mannosyltransferase   0.43842
Rv1411c lipoprotein lprG   0.43607
Rv0821c phosphate-transport system transcriptional regulator phoY2   0.43449
Rv1837c malate synthase G glcB   0.43381
Rv0931c transmembrane serine/threonine-protein kinase D pknD   0.43364
Rv1480 conserved hypothetical protein   0.43206
Rv1449c transketolase tkt   0.4318
Rv1828 conserved hypothetical protein   0.42094
Rv3284 conserved hypothetical protein   0.41931
Rv0490 two component system sensor histidine kinase senX3   0.41918
Rv1464 cysteine desulfurase csd   0.41914
Rv1595 L-aspartate oxidase nadB   0.41871
Rv1248c 2-oxoglutarate dehydrogenase sucA   0.41823
Rv3051c ribonucleoside-diphosphate reductase alpha chain nrdE   0.4172
Rv1821 preprotein translocase ATPase secA2   0.41562
Rv1332 transcriptional regulator   0.41529
Rv3869 conserved membrane protein   0.4139
Rv2753c dihydrodipicolinate synthase dapA   0.41157
Rv2576c conserved membrane protein   0.4111
Rv1465 nitrogen fixation related protein   0.40964
Rv1474c transcriptional regulator   0.406
Rv0860 fatty-acid oxidation protein fadB   0.40589
Rv2496c pyruvate dehydrogenase E1 component beta subunit pdhB   0.40503
Rv1328 glycogen phosphorylase glgP   0.40367
Rv2477c macrolide-transport ATP-binding protein ABC transporter   0.40267
Rv1446c oxpp cycle protein opcA   0.40006
Rv1783 conserved membrane protein   0.39876
Rv3800c polyketide synthase pks13   0.39844
Rv1462 conserved hypothetical protein   0.3983
Rv2583c GTP pyrophosphokinase relA   0.39807
Rv1916 isocitrate lyase aceAb   0.3973
Rv1324 thioredoxin   0.39703
Rv2051c polyprenol-monophosphomannose synthase ppm1   0.39688
Rv3627c conserved hypothetical protein   0.39529
Rv2790c lipid-transfer protein ltp1   0.39457
Rv3816c acyltransferase   0.39225
Rv1301 conserved hypothetical protein   0.39208
Rv1100 conserved hypothetical protein   0.39154
Rv0006 DNA gyrase subunit A gyrA   0.39106
Rv1110 lytB-related protein lytB2   0.39082
Rv3867 conserved hypothetical protein   0.38862
Rv3858c NADH-dependent glutamate synthase small subunit gltD   0.38727
Rv2224c exported protease   0.38606
Rv0423c thiamine biosynthesis protein thiC   0.38367
Rv2110c proteasome beta subunit prcB   0.38188
Rv0424c hypothetical protein   0.38047
Rv2134c conserved hypothetical protein   0.37969
Rv1461 conserved hypothetical protein   0.37861
Rv0512 delta-aminolevulinic acid dehydratase hemB   0.37837
Rv1223 serine protease htrA   0.37788
Rv1310 ATP synthase beta chain atpD   0.37624
Rv3283 thiosulfate sulfurtransferase sseA   0.37465
Rv0722 50S ribosomal protein L30 rpmD   0.37378
Rv0495c conserved hypothetical protein   0.37335
Rv2936 daunorubicin-dim-transport ATP-binding protein ABC transporter drrA   0.37287
Rv0290 conserved membrane protein   0.37261
Rv2613c conserved hypothetical protein   0.37135
Rv2587c protein-export membrane protein secD   0.37015
Rv2448c valyl-tRNA synthase protein valS   0.36933
Rv0050 bifunctional penicillin-binding protein ponA1   0.36876
Rv2743c conserved alanine rich membrane protein   0.36725
Rv1083 conserved hypothetical protein   0.36423
Rv1448c transaldolase tal   0.3622
Rv2788 transcriptional repressor sirR   0.36187
Rv3257c phosphomannomutase pmmA   0.36122
Rv3606c 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK   0.36115
Rv1638 excinuclease ABC subunit A uvrA   0.3605
Rv3030 conserved hypothetical protein   0.35988
Rv3044 Fe(III)-dicitrate-binding periplasmic lipoprotein fecB   0.35957
Rv2537c 3-dehydroquinate dehydratase aroD   0.35889
Rv2052c conserved hypothetical protein   0.35752
Rv3410c inosine-5-monophosphate dehydrogenase guaB3   0.35653
Rv3588c carbonic anhydrase   0.35583
Rv2181 conserved membrane protein   0.35481
Rv1340 ribonuclease rphA   0.3526
Rv3019c Esat-6 like protein esxR   0.3501
Rv1615 hypothetical membrane protein   0.34978
Rv2932 phenolpthiocerol synthesis type-I polyketide synthase ppsB   0.34951
Rv0270 fatty-acid-CoA ligase fadD2   0.34884
Rv1333 hydrolase   0.34852
Rv0958 magnesium chelatase   0.34688
Rv0710 30S ribosomal protein S17 rpsQ   0.34627
Rv2163c penicillin-binding membrane protein pbpB   0.34615
Rv3045 NADP-dependent alcohol dehydrogenase adhC   0.34572
Rv3264c D-alpha-D-mannose-1-phosphate guanylyltransferase manB   0.34447
Rv0299 hypothetical protein   0.34446
Rv1421 conserved hypothetical protein   0.34371
Rv2164c conserved proline rich membrane protein   0.34352
Rv1602 amidotransferase hisH   0.34292
Rv1594 quinolinate synthetase nadA   0.3428
Rv2152c UDP-N-acetylmuramate-alanine ligase murC   0.34237
Rv3813c conserved hypothetical protein   0.34155
Rv2916c signal recognition particle protein ffh   0.34064
Rv1416 riboflavin synthase beta chain ribH   0.34022
Rv1323 acetyl-CoA acetyltransferase fadA4   0.34009
Rv2614c threonyl-tRNA synthetase thrS   0.33936
Rv2092c ATP-dependent DNA helicase helY   0.33889
Rv2455c oxidoreductase alpha subunit   0.33833
Rv2703 RNA polymerase sigma factor sigA   0.33625
Rv1782 conserved membrane protein   0.33624
Rv3865 conserved hypothetical protein   0.33617
Rv0712 conserved hypothetical protein   0.33549
Rv2794c conserved hypothetical protein   0.33507
Rv2941 fatty-acid-CoA ligase fadD28   0.33475
Rv0411c glutamine-binding lipoprotein glnH   0.33434
Rv2791c transposase   0.33434
Rv2196 ubiquinol-cytochrome C reductase qcrB cytochrome B subunit   0.33432
Rv2678c uroporphyrinogen decarboxylase hemE   0.33431
Rv1604 inositol-monophosphatase impA   0.33423
Rv1463 ABC transporter ATP-binding protein   0.33421
Rv2219 conserved membrane protein   0.33406
Rv2841c N utilization substance protein A nusA   0.3338
Rv0410c serine/threonine-protein kinase pknG   0.33373
Rv0300 conserved hypothetical protein   0.33341
Rv1616 conserved membrane protein   0.33329
Rv3193c conserved membrane protein   0.33305
Rv2476c NAD-dependent glutamate dehydrogenase gdh   0.33259
Rv2202c carbohydrate kinase cbhK   0.33194
Rv3781 O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter rfbE   0.33171
Rv3161c dioxygenase   0.33156
Rv0932c periplasmic phosphate-binding lipoprotein pstS2   0.33083
Rv1274 lipoprotein lprB   0.33052
Rv2507 conserved proline rich membrane protein   0.32899
Rv0284 conserved membrane protein   0.32892
Rv0676c transmembrane transport protein mmpL5   0.32833
Rv3780 conserved hypothetical protein   0.32735
Rv2554c conserved hypothetical protein   0.32605
Rv2178c 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase aroG   0.32532
Rv3799c propionyl-CoA carboxylase beta chain 4 accD4   0.3248
Rv0528 conserved membrane protein   0.32471
Rv3879c hypothetical alanine and proline rich protein   0.32313
Rv2392 3-phosphoadenosine 5-phosphosulfate reductase cysH   0.32277
Rv2367c hypothetical protein   0.32277
Rv0289 conserved hypothetical protein   0.32179
Rv3815c acyltransferase   0.32098
Rv0351 chaperone grpE   0.32066
Rv3028c electron transfer flavoprotein alpha subunit fixB   0.3204
Rv2053c transmembrane protein   0.31909
Rv1600 histidinol-phosphate aminotransferase hisC1   0.31856
Rv2675c conserved hypothetical protein   0.31842
Rv0291 membrane-anchored mycosin mycP3   0.31821
Rv2838c ribosome-binding factor A rbfA   0.31799
Rv1126c conserved hypothetical protein   0.31786
Rv2611c acyltransferase   0.31742
Rv2461c ATP-dependent clp protease proteolytic subunit 1 clpP1   0.31723
Rv0353 merR-family heat shock protein transcriptional repressor hspR   0.31642
Rv3220c two component system sensor kinase   0.31421
Rv1309 ATP synthase gamma chain atpG   0.31382
Rv1122 6-phosphogluconate dehydrogenase, decarboxylating gnd2   0.31317
Rv3042c phosphoserine phosphatase serB2   0.31278
Rv3407 conserved hypothetical protein   0.31266
Rv3197 ABC transporter ATP-binding protein   0.31228
Rv0472c transcriptional regulator, tetR-family   0.31228
Rv1162 respiratory nitrate reductase beta chain narH   0.31177
Rv2453c molybdopterin-guanine dinucleotide biosynthesis protein A mobA   0.31083
Rv0350 chaperone protein dnaK   0.31034
Rv0247c succinate dehydrogenase iron-sulfur subunit   0.31012
Rv1224 hypothetical protein tatB   0.30972
Rv3607c dihydroneopterin aldolase folB   0.30937
Rv2710 RNA polymerase sigma factor sigB   0.30882
Rv0282 conserved hypothetical protein   0.30863
Rv0038 conserved hypothetical protein   0.30837
Rv3002c acetolactate synthase small subunit ilvN   0.30792
Rv0684 elongation factor G fusA1   0.30755
Rv2096c conserved hypothetical protein   0.30668
Rv2372c conserved hypothetical protein   0.30648
Rv0288 low molecular weight protein antigen 7 esxH   0.30619
Rv3520c coenzyme F420-dependent oxidoreductase   0.30515
Rv0206c transmembrane transport protein mmpL3   0.30476
Rv2474c conserved hypothetical protein   0.30475
Rv3020c Esat-6 like protein esxS   0.30459
Rv3592 conserved hypothetical protein   0.30414
Rv3805c conserved membrane protein   0.30362
Rv3408 conserved hypothetical protein   0.30273
Rv0525 conserved hypothetical protein   0.30269
Rv2553c conserved membrane protein   0.30244
Rv2859c amidotransferase   0.30214
Rv1872c L-lactate dehydrogenase lldD2   0.30095
Rv2604c conserved hypothetical protein   0.30089
Rv1173 F420 biosynthesis protein fbiC   0.30038
Rv3875 6 kda early secretory antigenic target esxA   0.30019