Correlation Catalog M. tuberculosis H37Rv: Rv0423c - thiamine biosynthesis protein thiC

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Distribution of gene correlation: Rv0423c vs. all genes ?
COG Categories ?

Information storage and processing

J Translation, ribosomal structure and biogenesis

K Transcription

I DNA replication, recombination and repair

Cellular Processes

D Cell division and chromosome partitioning

O Posttranslational modification, protein turnover, chaperones

M Cell envelope biogenesis, outer membrane

N Cell motility and secretion

P Inorganic transport and metabolism

T Signal transduction mechanisms

Metabolism

C Energy production and conversion

G Carbohydrate transport and metabolism

E Amino acid transport and metabolism

F Nucleotide transport and metabolism

H Coenzyme metabolism

I Lipid metabolism

Q Secondary metabolites biosynthesis, transport and catabolism

Poorly characterized

R General function predicton only

S Unknown function

X No COG assigned

Genes with negative correlation ?

 Categories Enriched ?: K

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv3183 transcriptional regulator   -0.47425
Rv1840c PE-PGRS family protein   -0.47296
Rv1929c conserved hypothetical protein   -0.44321
Rv3832c conserved hypothetical protein   -0.43204
Rv2306c   -0.42382
Rv2034 arsR-type repressor protein   -0.42333
Rv3180c hypothetical alanine rich protein   -0.42274
Rv2022c conserved hypothetical protein   -0.41219
Rv1044 conserved hypothetical protein   -0.41175
Rv3182 conserved hypothetical protein   -0.40469
Rv3488 conserved hypothetical protein   -0.40413
Rv0008c membrane protein   -0.40055
Rv2516c hypothetical protein   -0.39801
Rv1285 sulfate adenylyltransferase subunit 2 cysD   -0.39788
Rv3189 conserved hypothetical protein   -0.39681
Rv2099c PE family protein   -0.39518
Rv3188 conserved hypothetical protein   -0.39391
Rv3388 PE-PGRS family protein   -0.39297
Rv1450c PE-PGRS family protein   -0.39213
Rv1986 conserved membrane protein   -0.39156
Rv1988 methyltransferase   -0.39039
Rv3426 PPE family protein   -0.39039
Rv1963c tetR-family transcriptional repressor mce3R   -0.38782
Rv2827c hypothetical protein   -0.38709
Rv3385c conserved hypothetical protein   -0.38683
Rv3658c conserved membrane protein   -0.38547
Rv1831 hypothetical protein   -0.38405
Rv1960c conserved hypothetical protein   -0.38111
Rv2212 conserved hypothetical protein   -0.37889
Rv2656c phiRv2 phage protein   -0.37867
Rv3340 O-acetylhomoserine sulfhydrylase metC   -0.3778
Rv3018c PPE family protein   -0.37715
Rv0610c hypothetical protein   -0.37605
Rv2254c membrane protein   -0.37031
Rv2255c hypothetical protein   -0.37026
Rv1141c enoyl-CoA hydratase echA11   -0.36863
Rv1192 hypothetical protein   -0.36748
Rv2122c phosphoribosyl-AMP pyrophosphatase hisE   -0.36736
Rv2517c hypothetical protein   -0.36649
Rv1528c polyketide synthase associated protein papA4   -0.365
Rv2274c hypothetical protein   -0.36282
Rv0654 dioxygenase   -0.36232
Rv2662 hypothetical protein   -0.3618
Rv1088 PE family protein   -0.35775
Rv2887 transcriptional regulator   -0.35696
Rv0520 methyltransferase/methylase   -0.35532
Rv1356c hypothetical protein   -0.35528
Rv2019 hypothetical protein   -0.35456
Rv1928c short-chain type dehydrogenase/reductase   -0.35433
Rv2606c pyridoxine biosynthesis protein   -0.35321
Rv3334 transcriptional regulator, merR-family   -0.35234
Rv2075c hypothetical exported protein   -0.3521
Rv3844 transposase   -0.35093
Rv2116 lipoprotein lppK   -0.34978
Rv0328 transcriptional regulator, tetR/acrR-family   -0.34894
Rv0742 PE-PGRS family protein   -0.34829
Rv1067c PE-PGRS family protein   -0.34768
Rv0832 PE-PGRS family protein   -0.34768
Rv2464c DNA glycosylase   -0.34649
Rv0340 conserved hypothetical protein   -0.34648
Rv2872 conserved hypothetical protein   -0.34536
Rv1517 conserved membrane protein   -0.34534
Rv0749 conserved hypothetical protein   -0.34453
Rv2295 conserved hypothetical protein   -0.34329
Rv2657c phiRv2 phage protein   -0.34274
Rv1468c PE-PGRS family protein   -0.34148
Rv0026 conserved hypothetical protein   -0.34079
Rv0137c peptide methionine sulfoxide reductase msrA   -0.34079
Rv3348 transposase   -0.34045
Rv2142c hypothetical protein   -0.33647
Rv0767c conserved hypothetical protein   -0.33638
Rv2487c PE-PGRS family protein   -0.33634
Rv2332 NAD-dependent malate oxidoreductase mez   -0.33551
Rv2669 conserved hypothetical protein   -0.33501
Rv0841c   -0.33468
Rv1750c fatty-acid-CoA ligase fadD1   -0.33412
Rv3367 PE-PGRS family protein   -0.33392
Rv1150 transposase   -0.33342
Rv2660c hypothetical protein   -0.33161
Rv1897c conserved hypothetical protein   -0.33106
Rv0268c hypothetical protein   -0.33105
Rv1041c transposase   -0.32946
Rv3425 PPE family protein   -0.32894
Rv2645 hypothetical protein   -0.32851
Rv1665 chalcone synthase pks11   -0.32768
Rv0117 oxidative stress response regulatory protein oxyS   -0.32763
Rv0612 conserved hypothetical protein   -0.32756
Rv1875 conserved hypothetical protein   -0.32721
Rv1418 lipoprotein lprH   -0.32475
Rv3176c epoxide hydrolase mesT   -0.32456
Rv1951c conserved hypothetical protein   -0.32439
Rv2655c phiRv2 phage protein   -0.32391
Rv2021c transcriptional regulator   -0.32334
Rv0317c glycerophosphoryl diester phosphodiesterase glpQ2   -0.32249
Rv2878c soluble secreted antigen mpt53 precursor   -0.32057
Rv3012c glutamyl-tRNA(gln) amidotransferase subunit C gatC   -0.31959
Rv3902c hypothetical protein   -0.31929
Rv3384c conserved hypothetical protein   -0.31779
Rv3454 conserved membrane protein   -0.31696
Rv3122 hypothetical protein   -0.31662
Rv2104c conserved hypothetical protein   -0.31591
Rv0488 conserved membrane protein   -0.31577
Rv0648 alpha-mannosidase   -0.3153
Rv3903c hypothetical alanine and proline rich protein   -0.31522
Rv1325c PE-PGRS family protein   -0.31462
Rv1806 PE family protein   -0.3134
Rv0322 UDP-glucose 6-dehydrogenase udgA   -0.31285
Rv3428c transposase   -0.31144
Rv3745c conserved hypothetical protein   -0.31133
Rv2421c nicotinate-nucleotide adenylyltransferase nadD   -0.31039
Rv3898c conserved hypothetical protein   -0.31008
Rv2635 hypothetical protein   -0.30994
Rv3539 PPE family protein   -0.30956
Rv2631 conserved hypothetical protein   -0.309
Rv2307c conserved hypothetical protein   -0.30861
Rv3396c GMP synthase guaA   -0.30844
Rv3098c hypothetical protein   -0.30809
Rv3651 conserved hypothetical protein   -0.30727
Rv0842 conserved membrane protein   -0.3061
Rv0662c conserved hypothetical protein   -0.30575
Rv0335c PE family protein   -0.30575
Rv3124 transcriptional regulator   -0.30519
Rv3656c conserved hypothetical protein   -0.30516
Rv3652 PE-PGRS family protein   -0.30485
Rv0689c hypothetical protein   -0.30375
Rv2650c phiRv2 phage protein   -0.3037
Rv3047c hypothetical protein   -0.30287
Rv2035 conserved hypothetical protein   -0.30271
Rv1339 conserved hypothetical protein   -0.30237
Rv1946c lipoprotein lppG   -0.30152
Rv2269c hypothetical protein   -0.30114
Rv1227c transmembrane protein   -0.30095

Genes with positive correlation ?

 Categories Enriched ?: C D

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv3283 thiosulfate sulfurtransferase sseA   0.62808
Rv0479c conserved membrane protein   0.57716
Rv3240c preprotein translocase secA1   0.54905
Rv0247c succinate dehydrogenase iron-sulfur subunit   0.53863
Rv1843c inosine-5-monophosphate dehydrogenase guaB1   0.53696
Rv1310 ATP synthase beta chain atpD   0.52762
Rv1248c 2-oxoglutarate dehydrogenase sucA   0.52579
Rv1916 isocitrate lyase aceAb   0.52306
Rv3051c ribonucleoside-diphosphate reductase alpha chain nrdE   0.52185
Rv1309 ATP synthase gamma chain atpG   0.51429
Rv0421c conserved hypothetical protein   0.50762
Rv2097c conserved hypothetical protein   0.50265
Rv1771 oxidoreductase   0.49877
Rv2457c ATP-dependent clp protease ATP-binding subunit clpX   0.4987
Rv2061c conserved hypothetical protein   0.49332
Rv3719 conserved hypothetical protein   0.49184
Rv1411c lipoprotein lprG   0.48702
Rv2091c membrane protein   0.47892
Rv0005 DNA gyrase subunit B gyrB   0.47684
Rv1821 preprotein translocase ATPase secA2   0.47506
Rv3019c Esat-6 like protein esxR   0.46994
Rv1677 lipoprotein dsbF   0.46863
Rv3877 conserved membrane protein   0.46673
Rv3281 conserved hypothetical protein   0.46642
Rv0425c metal cation transporting P-type ATPase ctpH   0.4654
Rv1925 acyl-CoA ligase fadD31   0.46096
Rv1783 conserved membrane protein   0.45791
Rv3193c conserved membrane protein   0.45556
Rv0931c transmembrane serine/threonine-protein kinase D pknD   0.45549
Rv2325c conserved hypothetical protein   0.45351
Rv0066c isocitrate dehydrogenase icd2   0.45249
Rv1871c conserved hypothetical protein   0.44991
Rv2967c pyruvate carboxylase pca   0.44481
Rv1223 serine protease htrA   0.44291
Rv2941 fatty-acid-CoA ligase fadD28   0.43745
Rv0503c cyclopropane-fatty-acyl-phospholipid synthase 2 cmaA2   0.43722
Rv2195 Rieske iron-sulfur protein qcrA   0.43651
Rv2476c NAD-dependent glutamate dehydrogenase gdh   0.43548
Rv2507 conserved proline rich membrane protein   0.43492
Rv2895c mycobactin utilization protein viuB   0.43416
Rv3151 NADH dehydrogenase I chain G nuoG   0.4327
Rv2753c dihydrodipicolinate synthase dapA   0.43198
Rv1543 fatty-acyl-CoA reductase   0.42964
Rv1437 phosphoglycerate kinase pgk   0.42944
Rv3868 conserved hypothetical protein   0.42905
Rv0613c hypothetical protein   0.42285
Rv3284 conserved hypothetical protein   0.42171
Rv0934 periplasmic phosphate-binding lipoprotein pstS1   0.42045
Rv1438 triosephosphate isomerase tpi   0.41827
Rv2460c ATP-dependent clp protease proteolytic subunit 2 clpP2   0.41733
Rv1872c L-lactate dehydrogenase lldD2   0.41621
Rv0287 esat-6 like protein esxG   0.41475
Rv3910 conserved membrane protein   0.41417
Rv2969c conserved membrane protein   0.41397
Rv1311 ATP synthase epsilon chain atpC   0.41386
Rv2586c protein-export membrane protein secF   0.41352
Rv2587c protein-export membrane protein secD   0.41345
Rv1784 conserved hypothetical protein   0.41275
Rv1448c transaldolase tal   0.4082
Rv2483c bifunctionnal phospholipid biosynthesis enzyme plsC   0.40584
Rv0783c multidrug resistance membrane efflux protein emrB   0.40448
Rv2855 NADPH-dependent mycothiol reductase mtr   0.40412
Rv3876 conserved alanine and proline rich protein   0.40345
Rv1747 conserved transmembrane ATP-binding protein ABC transporter   0.40336
Rv1363c membrane protein   0.40238
Rv3690 conserved membrane protein   0.40135
Rv3496c MCE-family protein mce4D   0.40007
Rv3588c carbonic anhydrase   0.39894
Rv0049 conserved hypothetical protein   0.39841
Rv2109c proteasome alpha subunit prcA   0.39697
Rv0424c hypothetical protein   0.39535
Rv1447c glucose-6-phosphate 1-dehydrogenase zwf2   0.39484
Rv3720 fatty-acid synthase   0.39412
Rv3870 conserved membrane protein   0.39334
Rv0733 adenylate kinase adk   0.39283
Rv2611c acyltransferase   0.39225
Rv2163c penicillin-binding membrane protein pbpB   0.39179
Rv1215c conserved hypothetical protein   0.38907
Rv2083 conserved hypothetical protein   0.38866
Rv3045 NADP-dependent alcohol dehydrogenase adhC   0.38779
Rv3153 NADH dehydrogenase I chain I nuoI   0.38572
Rv1083 conserved hypothetical protein   0.38468
Rv2791c transposase   0.38461
Rv2475c conserved hypothetical protein   0.3842
Rv2868c 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase gcpE   0.38367
Rv1304 ATP synthase A chain atpB   0.38355
Rv1275 lipoprotein lprC   0.38237
Rv0288 low molecular weight protein antigen 7 esxH   0.38235
Rv1306 ATP synthase B chain atpF   0.38139
Rv0171 MCE-family protein mce1C   0.38119
Rv0289 conserved hypothetical protein   0.37924
Rv1703c catechol-O-methyltransferase   0.37858
Rv0174 MCE-family protein mce1F   0.37847
Rv0172 MCE-family protein mce1D   0.37722
Rv2215 pyruvate dehydrogenase E2 component sucB   0.37648
Rv1445c 6-phosphogluconolactonase devB   0.37646
Rv3157 NADH dehydrogenase I chain M nuoM   0.3756
Rv3781 O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter rfbE   0.37403
Rv3497c MCE-family protein mce4C   0.37203
Rv0018c serine/threonine phosphatase ppp   0.37181
Rv1410c aminoglycosides/tetracycline-transport membrane protein   0.37163
Rv3318 succinate dehydrogenase flavoprotein subunit sdhA   0.37038
Rv3149 NADH dehydrogenase I chain E nuoE   0.36995
Rv2881c membrane phosphatidate cytidylyltransferase cdsA   0.36994
Rv0284 conserved membrane protein   0.36875
Rv0490 two component system sensor histidine kinase senX3   0.3687
Rv3499c MCE-family protein mce4A   0.36795
Rv2461c ATP-dependent clp protease proteolytic subunit 1 clpP1   0.36763
Rv2199c conserved membrane protein   0.36702
Rv2427c gamma-glutamyl phosphate reductase protein proA   0.36701
Rv3887c conserved membrane protein   0.36628
Rv0111 transmembrane acyltransferase   0.36628
Rv1449c transketolase tkt   0.36571
Rv3814c acyltransferase   0.36549
Rv2703 RNA polymerase sigma factor sigA   0.36538
Rv3155 NADH dehydrogenase I chain K nuoK   0.36509
Rv0464c conserved hypothetical protein   0.36448
Rv2537c 3-dehydroquinate dehydratase aroD   0.36426
Rv3285 bifunctional acetyl-/propionyl-coenzyme A carboxylase alpha chain accA3   0.36024
Rv2773c dihydrodipicolinate reductase dapB   0.35973
Rv1615 hypothetical membrane protein   0.35942
Rv2822c hypothetical protein   0.35927
Rv1182 polyketide synthase associated protein papA3   0.35682
Rv2393 conserved hypothetical protein   0.35625
Rv0173 MCE-family lipoprotein mce1E   0.35579
Rv1307 ATP synthase delta chain atpH   0.35561
Rv1701 integrase   0.35554
Rv3495c MCE-family lipoprotein mce4E   0.35513
Rv0724 protease IV sppA   0.35509
Rv1023 enolase eno   0.35503
Rv3319 succinate dehydrogenase iron-sulphur protein subunit sdhB   0.35493
Rv0470c mycolic acid synthase pcaA   0.35463
Rv3800c polyketide synthase pks13   0.35438
Rv3692 methanol dehydrogenase transcriptional regulator moxR2   0.3542
Rv2082 conserved hypothetical protein   0.35357
Rv2454c oxidoreductase beta subunit   0.35356
Rv3867 conserved hypothetical protein   0.35224
Rv1596 nicotinate-nucleotide pyrophosphatase nadC   0.35198
Rv3791 short-chain type dehydrogenase/reductase   0.35181
Rv2207 nicotinate-nucleotide-dimethylbenzimidazol phosphoribosyltransferase cobT   0.35176
Rv0178 MCE-associated membrane protein   0.35043
Rv1126c conserved hypothetical protein   0.35043
Rv3815c acyltransferase   0.34965
Rv3853 S-adenosylmethionine:2-demethylmenaquinone methyltransferase menG   0.34786
Rv3215 isochorismate synthase entC   0.34686
Rv3147 NADH dehydrogenase I chain C nuoC   0.34666
Rv3020c Esat-6 like protein esxS   0.34649
Rv1836c conserved hypothetical protein   0.34545
Rv2219 conserved membrane protein   0.34472
Rv0006 DNA gyrase subunit A gyrA   0.34464
Rv3044 Fe(III)-dicitrate-binding periplasmic lipoprotein fecB   0.34361
Rv2942 transmembrane transport protein mmpL7   0.3428
Rv2367c hypothetical protein   0.34262
Rv1770 conserved hypothetical protein   0.34176
Rv2196 ubiquinol-cytochrome C reductase qcrB cytochrome B subunit   0.34176
Rv2453c molybdopterin-guanine dinucleotide biosynthesis protein A mobA   0.34132
Rv2613c conserved hypothetical protein   0.34128
Rv0495c conserved hypothetical protein   0.34012
Rv2127 L-asparagine permease ansP1   0.33931
Rv0041 leucyl-tRNA synthetase leuS   0.3393
Rv3412 conserved hypothetical protein   0.33909
Rv1479 transcriptional regulator moxR1   0.33878
Rv1097c glycine and proline rich membrane protein   0.33831
Rv0821c phosphate-transport system transcriptional regulator phoY2   0.33738
Rv0530 conserved hypothetical protein   0.33728
Rv1280c periplasmic oligopeptide-binding lipoprotein oppA   0.33682
Rv1608c peroxidoxin bcpB   0.33645
Rv3410c inosine-5-monophosphate dehydrogenase guaB3   0.33618
Rv0225 conserved hypothetical protein   0.33528
Rv1122 6-phosphogluconate dehydrogenase, decarboxylating gnd2   0.33309
Rv1823 conserved hypothetical protein   0.3329
Rv0169 MCE-family protein mce1A   0.33249
Rv3043c cytochrome C oxidase polypeptide I ctaD   0.33238
Rv3885c conserved membrane protein   0.33148
Rv0058 replicative DNA helicase dnaB   0.32961
Rv3852 histone-like protein hns   0.32798
Rv3596c ATP-dependent protease ATP-binding subunit clpC1   0.32797
Rv3813c conserved hypothetical protein   0.32783
Rv1070c enoyl-CoA hydratase echA8   0.32779
Rv2245 3-oxoacyl-[acyl-carrier protein] synthase 1 kasA   0.32712
Rv2775 hypothetical protein   0.32695
Rv2218 lipoate biosynthesis protein A lipA   0.32621
Rv1415 riboflavin biosynthesis protein ribA2   0.32603
Rv0868c molybdenum cofactor biosynthesis protein D 2 moaD2   0.32516
Rv1416 riboflavin synthase beta chain ribH   0.32493
Rv1038c Esat-6 like protein esxJ   0.3237
Rv1797 conserved hypothetical protein   0.32327
Rv1328 glycogen phosphorylase glgP   0.32316
Rv0014c transmembrane serine/threonine-protein kinase B pknB   0.32302
Rv1173 F420 biosynthesis protein fbiC   0.32298
Rv3682 bifunctional membrane-associated penicillin-binding protein 1A/1B ponA2   0.32289
Rv3799c propionyl-CoA carboxylase beta chain 4 accD4   0.32186
Rv1323 acetyl-CoA acetyltransferase fadA4   0.32175
Rv0208c methlytransferase   0.32079
Rv3884c cbxX/cfqX family protein   0.32049
Rv3703c conserved hypothetical protein   0.31961
Rv0050 bifunctional penicillin-binding protein ponA1   0.31887
Rv1274 lipoprotein lprB   0.31804
Rv1305 ATP synthase C chain atpE   0.31795
Rv1829 conserved hypothetical protein   0.31788
Rv1480 conserved hypothetical protein   0.31773
Rv1474c transcriptional regulator   0.31756
Rv1021 conserved hypothetical protein   0.31689
Rv3144c PPE family protein   0.31636
Rv3888c conserved membrane protein   0.31605
Rv0835 lipoprotein lpqQ   0.31542
Rv1185c fatty-acid-CoA ligase fadD21   0.3148
Rv2214c short-chain type dehydrogenase ephD   0.3148
Rv1074c beta-ketoacyl CoA thiolase fadA3   0.31449
Rv3626c conserved hypothetical protein   0.31345
Rv2392 3-phosphoadenosine 5-phosphosulfate reductase cysH   0.31331
Rv3291c transcriptional regulator, asnC-family   0.31215
Rv0417 thiamin biosynthesis protein thiG   0.31199
Rv1844c 6-phosphogluconate dehydrogenase gnd1   0.31186
Rv0292 conserved membrane protein   0.3111
Rv3871 conserved hypothetical protein   0.31085
Rv1915 isocitrate lyase aceAa   0.31042
Rv0227c conserved membrane protein   0.30926
Rv3865 conserved hypothetical protein   0.30863
Rv1837c malate synthase G glcB   0.30786
Rv2994 conserved membrane protein   0.30756
Rv3801c fatty-acid-CoA ligase fadD32   0.30705
Rv3869 conserved membrane protein   0.30675
Rv2200c transmembrane cytochrome C oxidase subunit II ctaC   0.30612
Rv1508c membrane protein   0.30491
Rv0183 lysophospholipase   0.30489
Rv2708c conserved hypothetical protein   0.3046
Rv2345 conserved membrane protein   0.30425
Rv2242 conserved hypothetical protein   0.30352
Rv0408 phosphate acetyltransferase pta   0.30342
Rv1421 conserved hypothetical protein   0.3034
Rv1793 esat-6 like protein esxN   0.30174
Rv0017c cell division protein rodA   0.30145
Rv1625c membrane-anchored adenylyl cyclase cya   0.30086
Rv0411c glutamine-binding lipoprotein glnH   0.30048
Rv3874 10 kda culture filtrate antigen esxB   0.30039
Rv1071c enoyl-CoA hydratase echA9   0.30023