Correlation Catalog M. tuberculosis H37Rv: Rv1223 - serine protease htrA

<< Rv1222
Rv1224 >>
Click on the question marks for explanations Hide help
Distribution of gene correlation: Rv1223 vs. all genes ?
COG Categories ?

Information storage and processing

J Translation, ribosomal structure and biogenesis

K Transcription

I DNA replication, recombination and repair

Cellular Processes

D Cell division and chromosome partitioning

O Posttranslational modification, protein turnover, chaperones

M Cell envelope biogenesis, outer membrane

N Cell motility and secretion

P Inorganic transport and metabolism

T Signal transduction mechanisms

Metabolism

C Energy production and conversion

G Carbohydrate transport and metabolism

E Amino acid transport and metabolism

F Nucleotide transport and metabolism

H Coenzyme metabolism

I Lipid metabolism

Q Secondary metabolites biosynthesis, transport and catabolism

Poorly characterized

R General function predicton only

S Unknown function

X No COG assigned

Genes with negative correlation ?

 Categories Enriched ?: None

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv0008c membrane protein   -0.47902
Rv2807 conserved hypothetical protein   -0.46773
Rv3021c PPE family protein   -0.44251
Rv1170 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase mshB   -0.42414
Rv1926c immunogenic protein mpt63   -0.41889
Rv1192 hypothetical protein   -0.41765
Rv1535 hypothetical protein   -0.41588
Rv2999 lipoprotein lppY   -0.41324
Rv0731c conserved hypothetical protein   -0.41172
Rv2068c class A beta-lactamase blaC   -0.41105
Rv0117 oxidative stress response regulatory protein oxyS   -0.40874
Rv2114 hypothetical protein   -0.40811
Rv0947c mycolyl transferase   -0.40724
Rv0317c glycerophosphoryl diester phosphodiesterase glpQ2   -0.40214
Rv2329c nitrite extrusion protein 1 narK1   -0.40057
Rv1944c conserved hypothetical protein   -0.3948
Rv2069 RNA polymerase sigma factor sigC   -0.39423
Rv2000 hypothetical protein   -0.39386
Rv3832c conserved hypothetical protein   -0.39338
Rv0730 conserved hypothetical protein   -0.39224
Rv3623 lipoprotein lpqG   -0.38864
Rv1960c conserved hypothetical protein   -0.38813
Rv1400c lipase lipH   -0.38459
Rv1516c sugar transferase   -0.38104
Rv3898c conserved hypothetical protein   -0.37814
Rv1227c transmembrane protein   -0.37729
Rv1141c enoyl-CoA hydratase echA11   -0.37237
Rv0322 UDP-glucose 6-dehydrogenase udgA   -0.36982
Rv2275 conserved hypothetical protein   -0.36696
Rv2019 hypothetical protein   -0.36567
Rv2288 hypothetical protein   -0.36485
Rv1285 sulfate adenylyltransferase subunit 2 cysD   -0.36465
Rv1951c conserved hypothetical protein   -0.3634
Rv3340 O-acetylhomoserine sulfhydrylase metC   -0.35804
Rv2723 conserved membrane protein   -0.35642
Rv2606c pyridoxine biosynthesis protein   -0.35453
Rv3425 PPE family protein   -0.35382
Rv0068 oxidoreductase   -0.35235
Rv0032 8-amino-7-oxononanoate synthase bioF2   -0.35048
Rv2996c D-3-phosphoglycerate dehydrogenase serA1   -0.34977
Rv3405c transcriptional regulator   -0.34655
Rv1750c fatty-acid-CoA ligase fadD1   -0.34644
Rv0090 membrane protein   -0.34499
Rv2691 trk system potassium uptake protein ceoB   -0.34453
Rv3218 conserved hypothetical protein   -0.34452
Rv0026 conserved hypothetical protein   -0.34351
Rv2645 hypothetical protein   -0.34106
Rv2959c methyltransferase/methylase   -0.34044
Rv1204c conserved hypothetical protein   -0.33921
Rv3391 acyl-CoA reductase acrA1   -0.33896
Rv1806 PE family protein   -0.33842
Rv2843 conserved alanine rich membrane protein   -0.33719
Rv3747 conserved hypothetical protein   -0.33507
Rv1807 PPE family protein   -0.33189
Rv1202 succinyl-diaminopimelate desuccinylase dapE   -0.3308
Rv2363 amidase amiA2   -0.33072
Rv2122c phosphoribosyl-AMP pyrophosphatase hisE   -0.33022
Rv0420c transmembrane protein   -0.32934
Rv1041c transposase   -0.3289
Rv2421c nicotinate-nucleotide adenylyltransferase nadD   -0.32793
Rv3129 conserved hypothetical protein   -0.32706
Rv0002 DNA polymerase III beta chain dnaN   -0.32696
Rv2274c hypothetical protein   -0.32691
Rv0887c conserved hypothetical protein   -0.32433
Rv3454 conserved membrane protein   -0.32412
Rv3797 acyl-CoA dehydrogenase fadE35   -0.3237
Rv2948c fatty-acid-CoA ligase fadD22   -0.32297
Rv3820c polyketide synthase associated protein papA2   -0.32184
Rv2049c hypothetical protein   -0.3214
Rv3008 hypothetical protein   -0.32134
Rv0533c 3-oxoacyl-[acyl-carrier-protein] synthase III fabH   -0.32123
Rv0643c methoxy mycolic acid synthase 3 mmaA3   -0.32045
Rv1428c conserved hypothetical protein   -0.32045
Rv2272 conserved membrane protein   -0.31982
Rv2638 conserved hypothetical protein   -0.31903
Rv3183 transcriptional regulator   -0.31827
Rv3803c secreted fibronectin-binding protein antigen protein fbpD   -0.31808
Rv1707 conserved membrane protein   -0.31675
Rv1897c conserved hypothetical protein   -0.31538
Rv2120c conserved membrane protein   -0.31537
Rv0122 hypothetical protein   -0.31535
Rv2716 conserved hypothetical protein   -0.31524
Rv2067c conserved hypothetical protein   -0.31447
Rv0942 hypothetical protein   -0.31366
Rv1143 alpha-methylacyl-CoA racemase mcr   -0.31291
Rv0780 phosphoribosylaminoimidazole-succinocarboxamide synthase purC   -0.31272
Rv1418 lipoprotein lprH   -0.31272
Rv3737 conserved membrane protein   -0.3121
Rv0151c PE family protein   -0.31122
Rv1517 conserved membrane protein   -0.31122
Rv3513c fatty-acid-CoA ligase fadD18   -0.31007
Rv0488 conserved membrane protein   -0.31003
Rv0951 succinyl-CoA synthetase beta chain sucC   -0.30982
Rv0256c PPE family protein   -0.30919
Rv0891c transcriptional regulator   -0.307
Rv2023c hypothetical protein   -0.30694
Rv2991 conserved hypothetical protein   -0.30446
Rv3108 hypothetical protein   -0.30426
Rv0394c secreted protein   -0.30379
Rv1929c conserved hypothetical protein   -0.30337
Rv0330c hypothetical protein   -0.30282
Rv3597c iron-regulated lsr2 protein precursor   -0.30278
Rv1176c conserved hypothetical protein   -0.30164
Rv3738c PPE family protein   -0.30117
Rv2121c ATP phosphoribosyltransferase hisG   -0.30101
Rv3788 hypothetical protein   -0.3003
Rv3658c conserved membrane protein   -0.3

Genes with positive correlation ?

 Categories Enriched ?: M N D

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv1224 hypothetical protein tatB   0.64694
Rv2367c hypothetical protein   0.59507
Rv2537c 3-dehydroquinate dehydratase aroD   0.57401
Rv3051c ribonucleoside-diphosphate reductase alpha chain nrdE   0.55997
Rv3868 conserved hypothetical protein   0.55639
Rv1843c inosine-5-monophosphate dehydrogenase guaB1   0.55507
Rv2109c proteasome alpha subunit prcA   0.54276
Rv0724 protease IV sppA   0.54266
Rv3877 conserved membrane protein   0.53748
Rv1416 riboflavin synthase beta chain ribH   0.52541
Rv0479c conserved membrane protein   0.52447
Rv3283 thiosulfate sulfurtransferase sseA   0.52086
Rv3876 conserved alanine and proline rich protein   0.51848
Rv1332 transcriptional regulator   0.51594
Rv2942 transmembrane transport protein mmpL7   0.51173
Rv2368c phosphate starvation-inducible protein phoH1   0.49516
Rv3244c lipoprotein lpqB   0.49429
Rv3284 conserved hypothetical protein   0.49225
Rv1083 conserved hypothetical protein   0.49112
Rv1916 isocitrate lyase aceAb   0.49016
Rv3608c dihydropteroate synthase 1 folp   0.48936
Rv0005 DNA gyrase subunit B gyrB   0.48929
Rv1925 acyl-CoA ligase fadD31   0.48774
Rv2507 conserved proline rich membrane protein   0.48667
Rv1126c conserved hypothetical protein   0.48276
Rv2325c conserved hypothetical protein   0.48227
Rv2163c penicillin-binding membrane protein pbpB   0.48166
Rv2753c dihydrodipicolinate synthase dapA   0.48143
Rv3606c 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK   0.48106
Rv2711 iron-dependent repressor and activator ideR   0.47361
Rv2097c conserved hypothetical protein   0.46956
Rv3720 fatty-acid synthase   0.46597
Rv2372c conserved hypothetical protein   0.46516
Rv3197 ABC transporter ATP-binding protein   0.4631
Rv1411c lipoprotein lprG   0.46146
Rv1335 9.5 kda culture filtrate antigen cfp10a   0.46041
Rv2586c protein-export membrane protein secF   0.45702
Rv0931c transmembrane serine/threonine-protein kinase D pknD   0.45489
Rv1596 nicotinate-nucleotide pyrophosphatase nadC   0.45446
Rv3870 conserved membrane protein   0.45401
Rv3240c preprotein translocase secA1   0.45305
Rv2553c conserved membrane protein   0.45281
Rv0411c glutamine-binding lipoprotein glnH   0.44952
Rv0821c phosphate-transport system transcriptional regulator phoY2   0.44922
Rv3719 conserved hypothetical protein   0.44867
Rv0868c molybdenum cofactor biosynthesis protein D 2 moaD2   0.44677
Rv3103c hypothetical proline rich protein   0.44488
Rv0423c thiamine biosynthesis protein thiC   0.44291
Rv3609c GTP cyclohydrolase I folE   0.44247
Rv1334 conserved hypothetical protein   0.44205
Rv3626c conserved hypothetical protein   0.44197
Rv2091c membrane protein   0.43958
Rv2053c transmembrane protein   0.43955
Rv2092c ATP-dependent DNA helicase helY   0.43835
Rv3871 conserved hypothetical protein   0.43701
Rv1798 conserved hypothetical protein   0.43482
Rv3161c dioxygenase   0.43369
Rv1333 hydrolase   0.43202
Rv0410c serine/threonine-protein kinase pknG   0.43076
Rv1821 preprotein translocase ATPase secA2   0.43023
Rv2483c bifunctionnal phospholipid biosynthesis enzyme plsC   0.43003
Rv1310 ATP synthase beta chain atpD   0.42719
Rv1615 hypothetical membrane protein   0.426
Rv3802c conserved membrane protein   0.42405
Rv2153c UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase murG   0.42277
Rv2941 fatty-acid-CoA ligase fadD28   0.42089
Rv3869 conserved membrane protein   0.4206
Rv3412 conserved hypothetical protein   0.41835
Rv1836c conserved hypothetical protein   0.41738
Rv3837c phosphoglycerate mutase   0.41699
Rv3800c polyketide synthase pks13   0.41579
Rv2444c ribonuclease E rne   0.4151
Rv2750 dehydrogenase   0.41426
Rv3410c inosine-5-monophosphate dehydrogenase guaB3   0.41047
Rv1217c tetronasin-transport membrane protein ABC transporter   0.40882
Rv1410c aminoglycosides/tetracycline-transport membrane protein   0.40826
Rv3879c hypothetical alanine and proline rich protein   0.40799
Rv2151c cell division protein ftsQ   0.40788
Rv2152c UDP-N-acetylmuramate-alanine ligase murC   0.40749
Rv1497 esterase lipL   0.4068
Rv3151 NADH dehydrogenase I chain G nuoG   0.40598
Rv2052c conserved hypothetical protein   0.4046
Rv3690 conserved membrane protein   0.40429
Rv0503c cyclopropane-fatty-acyl-phospholipid synthase 2 cmaA2   0.40379
Rv3256c conserved hypothetical protein   0.4036
Rv2583c GTP pyrophosphokinase relA   0.40244
Rv0676c transmembrane transport protein mmpL5   0.40226
Rv1479 transcriptional regulator moxR1   0.40219
Rv3815c acyltransferase   0.40117
Rv1540 conserved hypothetical protein   0.39846
Rv2743c conserved alanine rich membrane protein   0.39483
Rv1784 conserved hypothetical protein   0.39434
Rv1478 invasion-associated protein   0.39415
Rv1700 conserved hypothetical protein   0.38927
Rv1110 lytB-related protein lytB2   0.3886
Rv0983 serine protease pepD   0.38809
Rv3193c conserved membrane protein   0.38742
Rv2457c ATP-dependent clp protease ATP-binding subunit clpX   0.3872
Rv2051c polyprenol-monophosphomannose synthase ppm1   0.38671
Rv2791c transposase   0.38589
Rv3212 conserved alanine and valine rich protein   0.38463
Rv0051 conserved membrane protein   0.38345
Rv2460c ATP-dependent clp protease proteolytic subunit 2 clpP2   0.38332
Rv0451c membrane protein mmpS4   0.38191
Rv1603 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase hisA   0.38003
Rv1445c 6-phosphogluconolactonase devB   0.37904
Rv1606 phosphoribosyl-AMP-1,6-cyclohydrolase hisI   0.37892
Rv0421c conserved hypothetical protein   0.37883
Rv0179c lipoprotein lprO   0.37831
Rv3339c isocitrate dehydrogenase icd1   0.37818
Rv1797 conserved hypothetical protein   0.37798
Rv2868c 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase gcpE   0.37788
Rv2752c conserved hypothetical protein   0.37587
Rv0178 MCE-associated membrane protein   0.37442
Rv0865 molybdopterin biosynthesis protein mog   0.37389
Rv1871c conserved hypothetical protein   0.37354
Rv1771 oxidoreductase   0.37346
Rv2967c pyruvate carboxylase pca   0.37253
Rv2454c oxidoreductase beta subunit   0.37154
Rv1300 hypothetical protein hemK   0.37129
Rv1164 respiratory nitrate reductase gamma chain narI   0.37103
Rv2365c conserved hypothetical protein   0.37057
Rv2135c conserved hypothetical protein   0.36898
Rv3519 hypothetical protein   0.36821
Rv1309 ATP synthase gamma chain atpG   0.36768
Rv3149 NADH dehydrogenase I chain E nuoE   0.36488
Rv1602 amidotransferase hisH   0.36462
Rv1701 integrase   0.36443
Rv0207c conserved hypothetical protein   0.36395
Rv1601 imidazole glycerol-phosphate dehydratase hisB   0.36376
Rv2484c conserved hypothetical protein   0.36253
Rv2687c antibiotic-transport membrane leucine and valine rich protein ABC transporter   0.36062
Rv0981 mycobacterial persistence regulator mprA   0.36057
Rv3588c carbonic anhydrase   0.36018
Rv1480 conserved hypothetical protein   0.35958
Rv1447c glucose-6-phosphate 1-dehydrogenase zwf2   0.3592
Rv1248c 2-oxoglutarate dehydrogenase sucA   0.35909
Rv3856c conserved hypothetical protein   0.3585
Rv2675c conserved hypothetical protein   0.35752
Rv2495c dihydrolipoamide S-acetyltransferase E2 component pdhC   0.3564
Rv0530 conserved hypothetical protein   0.35618
Rv2682c 1-deoxy-D-xylulose 5-phosphate synthase dxs1   0.35589
Rv0247c succinate dehydrogenase iron-sulfur subunit   0.35548
Rv2703 RNA polymerase sigma factor sigA   0.35357
Rv3865 conserved hypothetical protein   0.35353
Rv3610c membrane-bound ell division protein ftsH   0.35263
Rv1222 conserved hypothetical protein   0.352
Rv0239 conserved hypothetical protein   0.35176
Rv3019c Esat-6 like protein esxR   0.35145
Rv3209 conserved proline and threonine rich protein   0.35002
Rv3496c MCE-family protein mce4D   0.34934
Rv2611c acyltransferase   0.34928
Rv3706c conserved proline rich protein   0.349
Rv0346c L-asparagine permease ansP2   0.34884
Rv1625c membrane-anchored adenylyl cyclase cya   0.34863
Rv2587c protein-export membrane protein secD   0.34735
Rv0050 bifunctional penicillin-binding protein ponA1   0.34674
Rv2554c conserved hypothetical protein   0.34642
Rv2134c conserved hypothetical protein   0.34556
Rv1025 conserved hypothetical protein   0.34545
Rv0006 DNA gyrase subunit A gyrA   0.34537
Rv0835 lipoprotein lpqQ   0.34486
Rv2165c conserved hypothetical protein   0.34465
Rv1421 conserved hypothetical protein   0.34408
Rv1906c conserved hypothetical protein   0.3439
Rv1677 lipoprotein dsbF   0.34231
Rv0208c methlytransferase   0.34226
Rv3767c conserved hypothetical protein   0.34211
Rv0381c hypothetical protein   0.34178
Rv0490 two component system sensor histidine kinase senX3   0.34149
Rv3593 lipoprotein lpqF   0.34144
Rv2164c conserved proline rich membrane protein   0.34131
Rv3799c propionyl-CoA carboxylase beta chain 4 accD4   0.34117
Rv3257c phosphomannomutase pmmA   0.34023
Rv1872c L-lactate dehydrogenase lldD2   0.34023
Rv2869c conserved membrane protein   0.33899
Rv0018c serine/threonine phosphatase ppp   0.33869
Rv1086 short-chain Z-isoprenyl diphosphate synthase   0.33771
Rv0183 lysophospholipase   0.33603
Rv1829 conserved hypothetical protein   0.33549
Rv0960 conserved hypothetical protein   0.33505
Rv1604 inositol-monophosphatase impA   0.33489
Rv1783 conserved membrane protein   0.3347
Rv1121 glucose-6-phosphate 1-dehydrogenase zwf1   0.33399
Rv1770 conserved hypothetical protein   0.33384
Rv1564c maltooligosyltrehalose synthase treX   0.33236
Rv1565c conserved membrane protein   0.33134
Rv1323 acetyl-CoA acetyltransferase fadA4   0.33105
Rv0014c transmembrane serine/threonine-protein kinase B pknB   0.33081
Rv2589 4-aminobutyrate aminotransferase gabT   0.33046
Rv1600 histidinol-phosphate aminotransferase hisC1   0.32974
Rv0425c metal cation transporting P-type ATPase ctpH   0.32929
Rv1782 conserved membrane protein   0.32922
Rv0292 conserved membrane protein   0.32908
Rv2613c conserved hypothetical protein   0.32843
Rv0934 periplasmic phosphate-binding lipoprotein pstS1   0.32841
Rv1162 respiratory nitrate reductase beta chain narH   0.32718
Rv3044 Fe(III)-dicitrate-binding periplasmic lipoprotein fecB   0.32682
Rv2154c cell division protein ftsW   0.32675
Rv1846c transcriptional regulator   0.32629
Rv3281 conserved hypothetical protein   0.32619
Rv2901c conserved hypothetical protein   0.32486
Rv0383c conserved secreted protein   0.32409
Rv2849c cob(I)alamin adenosyltransferase cobO   0.32177
Rv3910 conserved membrane protein   0.32175
Rv2218 lipoate biosynthesis protein A lipA   0.32164
Rv3413c hypothetical alanine and proline rich protein   0.32093
Rv1027c transcriptional regulator kdpE   0.32091
Rv3042c phosphoserine phosphatase serB2   0.32081
Rv0181c conserved hypothetical protein   0.32065
Rv1122 6-phosphogluconate dehydrogenase, decarboxylating gnd2   0.32
Rv2476c NAD-dependent glutamate dehydrogenase gdh   0.31963
Rv3682 bifunctional membrane-associated penicillin-binding protein 1A/1B ponA2   0.31954
Rv1074c beta-ketoacyl CoA thiolase fadA3   0.31938
Rv3313c adenosine deaminase add   0.31929
Rv3147 NADH dehydrogenase I chain C nuoC   0.31923
Rv2131c monophosphatase cysQ   0.31727
Rv0590 MCE-family protein mce2B   0.31693
Rv2326c transmembrane ATP-binding protein ABC transorter   0.31689
Rv2094c SEC-independent protein translocase membrane-bound protein tatA   0.31676
Rv1477 invasion-associated protein   0.31634
Rv0284 conserved membrane protein   0.31604
Rv2115c ATPase   0.31584
Rv2905 alanine rich lipoprotein lppW   0.31465
Rv1102c conserved hypothetical protein   0.31369
Rv2219 conserved membrane protein   0.31337
Rv3818 hypothetical protein   0.31276
Rv2681 conserved alanine rich protein   0.31275
Rv3272 conserved hypothetical protein   0.31238
Rv2538c 3-dehydroquinate synthase aroB   0.3119
Rv1218c tetronasin-transport ATP-binding protein ABC transporter   0.31171
Rv1862 alcohol dehydrogenase adhA   0.31014
Rv1005c para-aminobenzoate synthase component I pabD   0.30995
Rv1619 conserved membrane protein   0.30989
Rv3436c glucosamine-fructose-6-phosphate aminotransferase glmS   0.30971
Rv1656 ornithine carbamoyltransferase argF   0.30862
Rv1100 conserved hypothetical protein   0.30846
Rv3813c conserved hypothetical protein   0.30813
Rv2969c conserved membrane protein   0.30775
Rv1594 quinolinate synthetase nadA   0.30741
Rv2680 conserved hypothetical protein   0.30734
Rv2614c threonyl-tRNA synthetase thrS   0.30565
Rv1747 conserved transmembrane ATP-binding protein ABC transporter   0.30552
Rv3200c transmembrane cation transporter   0.3044
Rv2181 conserved membrane protein   0.30226
Rv2228c conserved hypothetical protein   0.30157
Rv1616 conserved membrane protein   0.30137
Rv1446c oxpp cycle protein opcA   0.30117
Rv2110c proteasome beta subunit prcB   0.30087
Rv0679c conserved threonine rich protein   0.30073
Rv0289 conserved hypothetical protein   0.30071
Rv0282 conserved hypothetical protein   0.30067
Rv2678c uroporphyrinogen decarboxylase hemE   0.30054
Rv2881c membrane phosphatidate cytidylyltransferase cdsA   0.30012
Rv0877 conserved hypothetical protein   0.30004