Correlation Catalog M. tuberculosis H37Rv: Rv2678c - uroporphyrinogen decarboxylase hemE

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Distribution of gene correlation: Rv2678c vs. all genes ?
COG Categories ?

Information storage and processing

J Translation, ribosomal structure and biogenesis

K Transcription

I DNA replication, recombination and repair

Cellular Processes

D Cell division and chromosome partitioning

O Posttranslational modification, protein turnover, chaperones

M Cell envelope biogenesis, outer membrane

N Cell motility and secretion

P Inorganic transport and metabolism

T Signal transduction mechanisms

Metabolism

C Energy production and conversion

G Carbohydrate transport and metabolism

E Amino acid transport and metabolism

F Nucleotide transport and metabolism

H Coenzyme metabolism

I Lipid metabolism

Q Secondary metabolites biosynthesis, transport and catabolism

Poorly characterized

R General function predicton only

S Unknown function

X No COG assigned

Genes with negative correlation ?

 Categories Enriched ?: J

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv2021c transcriptional regulator   -0.44078
Rv2764c thymidylate synthase thyA   -0.41906
Rv1926c immunogenic protein mpt63   -0.41552
Rv3363c conserved hypothetical protein   -0.40076
Rv2253 secreted protein   -0.39188
Rv2114 hypothetical protein   -0.39074
Rv2807 conserved hypothetical protein   -0.38987
Rv1402 primosomal protein N priA   -0.38874
Rv1956 transcriptional regulator   -0.38666
Rv3820c polyketide synthase associated protein papA2   -0.38604
Rv3218 conserved hypothetical protein   -0.38366
Rv3789 conserved membrane protein   -0.38248
Rv1960c conserved hypothetical protein   -0.3811
Rv1980c immunogenic protein mpt64   -0.37918
Rv3924c 50S ribosomal protein L34 rpmH   -0.37901
Rv0643c methoxy mycolic acid synthase 3 mmaA3   -0.37769
Rv1535 hypothetical protein   -0.37703
Rv2075c hypothetical exported protein   -0.37005
Rv0739 conserved hypothetical protein   -0.36972
Rv3488 conserved hypothetical protein   -0.36858
Rv2000 hypothetical protein   -0.36616
Rv2907c 16S rRNA processing protein rimM   -0.36554
Rv3745c conserved hypothetical protein   -0.36463
Rv3898c conserved hypothetical protein   -0.36241
Rv2713 soluble pyridine nucleotide transhydrogenase sthA   -0.36011
Rv0256c PPE family protein   -0.35839
Rv2999 lipoprotein lppY   -0.35719
Rv0610c hypothetical protein   -0.35618
Rv2023c hypothetical protein   -0.355
Rv1957 hypothetical protein   -0.35398
Rv1806 PE family protein   -0.35298
Rv2563 glutamine-transport transmembrane protein ABC transporter   -0.35271
Rv1270c lipoprotein lprA   -0.35227
Rv1988 methyltransferase   -0.3498
Rv3890c Esat-6 like protein esxC   -0.34739
Rv1516c sugar transferase   -0.34527
Rv3521 conserved hypothetical protein   -0.34339
Rv0947c mycolyl transferase   -0.34185
Rv2960c hypothetical protein   -0.34003
Rv1944c conserved hypothetical protein   -0.33982
Rv3788 hypothetical protein   -0.33978
Rv1807 PPE family protein   -0.33947
Rv0117 oxidative stress response regulatory protein oxyS   -0.33882
Rv1876 bacterioferritin bfrA   -0.33707
Rv2441c 50S ribosomal protein L27 rpmA   -0.33378
Rv3425 PPE family protein   -0.33193
Rv0055 30S ribosomal protein rpsR1   -0.33096
Rv0583c lipoprotein lpqN   -0.32873
Rv2019 hypothetical protein   -0.32836
Rv3797 acyl-CoA dehydrogenase fadE35   -0.3278
Rv3391 acyl-CoA reductase acrA1   -0.32736
Rv1951c conserved hypothetical protein   -0.3264
Rv2018 conserved hypothetical protein   -0.32622
Rv2057c 50S ribosomal protein L33   -0.32347
Rv0780 phosphoribosylaminoimidazole-succinocarboxamide synthase purC   -0.32316
Rv2954c hypothetical protein   -0.32194
Rv2421c nicotinate-nucleotide adenylyltransferase nadD   -0.32054
Rv0873 acyl-CoA dehydrogenase fadE10   -0.32012
Rv2055c 30S ribosomal protein S18 rpsR2   -0.31916
Rv3715c recombination protein recR   -0.31911
Rv2755c Type I restriction/modification system specificity determinant hsdS_1   -0.31887
Rv2909c 30S ribosomal protein S16 rpsP   -0.31824
Rv2329c nitrite extrusion protein 1 narK1   -0.31766
Rv2699c conserved hypothetical protein   -0.31739
Rv2873 cell surface lipoprotein mpt83   -0.31737
Rv3683 conserved hypothetical protein   -0.31734
Rv3143 response regulator   -0.3172
Rv0231 acyl-CoA dehydrogenase fadE4   -0.31705
Rv2959c methyltransferase/methylase   -0.31667
Rv3443c 50S ribosomal protein L13 rplM   -0.31576
Rv3639c conserved hypothetical protein   -0.31543
Rv2022c conserved hypothetical protein   -0.31475
Rv2442c 50S ribosomal protein L21 rplU   -0.31369
Rv1984c cutinase precursor cfp21   -0.31338
Rv2669 conserved hypothetical protein   -0.31165
Rv1018c UDP-N-acetylglucosamine pyrophosphorylase glmU   -0.31118
Rv2122c phosphoribosyl-AMP pyrophosphatase hisE   -0.30947
Rv3481c membrane protein   -0.3089
Rv3674c endonuclease III nth   -0.3089
Rv1873 conserved hypothetical protein   -0.30883
Rv1707 conserved membrane protein   -0.30862
Rv2301 cutinase cut2   -0.30782
Rv2723 conserved membrane protein   -0.30719
Rv0701 50S ribosomal protein L3 rplC   -0.30701
Rv3528c hypothetical protein   -0.30668
Rv1206 fatty-acid-CoA ligase fadD6   -0.30427
Rv0008c membrane protein   -0.30393
Rv3547 conserved hypothetical protein   -0.30276
Rv3721c DNA polymerase III gamma/tau subunit dnaZ/X   -0.30238
Rv0781 protease II ptrBa   -0.30066

Genes with positive correlation ?

 Categories Enriched ?: E M

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv1100 conserved hypothetical protein   0.59175
Rv1540 conserved hypothetical protein   0.49169
Rv1126c conserved hypothetical protein   0.48871
Rv1603 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase hisA   0.48849
Rv1916 isocitrate lyase aceAb   0.4874
Rv2230c conserved hypothetical protein   0.48658
Rv2470 oxygen-binding protein globin glbO   0.48584
Rv2610c alpha-mannosyltransferase pimA   0.4805
Rv3626c conserved hypothetical protein   0.47813
Rv2109c proteasome alpha subunit prcA   0.47284
Rv1602 amidotransferase hisH   0.4723
Rv1539 lipoprotein signal peptidase lspA   0.46864
Rv0875c hypothetical exported protein   0.46373
Rv0865 molybdopterin biosynthesis protein mog   0.46315
Rv1122 6-phosphogluconate dehydrogenase, decarboxylating gnd2   0.46065
Rv1410c aminoglycosides/tetracycline-transport membrane protein   0.45579
Rv1333 hydrolase   0.45373
Rv1480 conserved hypothetical protein   0.45371
Rv0038 conserved hypothetical protein   0.44869
Rv1700 conserved hypothetical protein   0.44658
Rv3244c lipoprotein lpqB   0.44506
Rv0411c glutamine-binding lipoprotein glnH   0.44238
Rv0528 conserved membrane protein   0.44061
Rv1121 glucose-6-phosphate 1-dehydrogenase zwf1   0.43855
Rv0931c transmembrane serine/threonine-protein kinase D pknD   0.43795
Rv0410c serine/threonine-protein kinase pknG   0.43224
Rv3256c conserved hypothetical protein   0.43204
Rv3813c conserved hypothetical protein   0.43198
Rv0958 magnesium chelatase   0.43043
Rv2326c transmembrane ATP-binding protein ABC transorter   0.42794
Rv3806c conserved membrane protein   0.42735
Rv0975c acyl-CoA dehydrogenase fadE13   0.42696
Rv1925 acyl-CoA ligase fadD31   0.42658
Rv1406 methionyl-tRNA formyltransferase fmt   0.42511
Rv2181 conserved membrane protein   0.42237
Rv1332 transcriptional regulator   0.42116
Rv0486 mannosyltransferase   0.41943
Rv0491 two component system sensor protein regX3   0.41786
Rv1606 phosphoribosyl-AMP-1,6-cyclohydrolase hisI   0.41705
Rv2152c UDP-N-acetylmuramate-alanine ligase murC   0.41525
Rv1086 short-chain Z-isoprenyl diphosphate synthase   0.41493
Rv2133c conserved hypothetical protein   0.41485
Rv1845c conserved membrane protein   0.41463
Rv2848c cobyrinic acid a,c-diamide synthase cobB   0.41336
Rv3042c phosphoserine phosphatase serB2   0.41002
Rv2153c UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase murG   0.40989
Rv2614c threonyl-tRNA synthetase thrS   0.40943
Rv2064 cobalamin biosynthesis protein cobG   0.4087
Rv3609c GTP cyclohydrolase I folE   0.40804
Rv3606c 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK   0.40781
Rv1007c methionyl-tRNA synthetase metS   0.40547
Rv0876c conserved membrane protein   0.40515
Rv0412c conserved membrane protein   0.40151
Rv2992c glutamyl-tRNA synthetase gltS   0.39988
Rv3627c conserved hypothetical protein   0.39951
Rv3758c osmoprotectant proV   0.39892
Rv0014c transmembrane serine/threonine-protein kinase B pknB   0.3983
Rv3422c conserved hypothetical protein   0.39634
Rv2151c cell division protein ftsQ   0.39603
Rv3284 conserved hypothetical protein   0.39568
Rv3856c conserved hypothetical protein   0.39516
Rv1843c inosine-5-monophosphate dehydrogenase guaB1   0.39512
Rv3410c inosine-5-monophosphate dehydrogenase guaB3   0.39453
Rv2438c glutamine-dependent NAD(+) synthetase nadE   0.39439
Rv3870 conserved membrane protein   0.39389
Rv2365c conserved hypothetical protein   0.39324
Rv1416 riboflavin synthase beta chain ribH   0.39145
Rv2367c hypothetical protein   0.38862
Rv0764c cytochrome P450 51 cyp51   0.38861
Rv1411c lipoprotein lprG   0.38728
Rv2092c ATP-dependent DNA helicase helY   0.38559
Rv1596 nicotinate-nucleotide pyrophosphatase nadC   0.38288
Rv1656 ornithine carbamoyltransferase argF   0.38251
Rv0983 serine protease pepD   0.38093
Rv2682c 1-deoxy-D-xylulose 5-phosphate synthase dxs1   0.37992
Rv1846c transcriptional regulator   0.37785
Rv2110c proteasome beta subunit prcB   0.37769
Rv0495c conserved hypothetical protein   0.37749
Rv3306c amidohydrolase amiB1   0.37693
Rv2131c monophosphatase cysQ   0.37692
Rv0490 two component system sensor histidine kinase senX3   0.37571
Rv3608c dihydropteroate synthase 1 folp   0.37443
Rv2589 4-aminobutyrate aminotransferase gabT   0.37287
Rv0382c orotate phosphoribosyltransferase pyrE   0.37207
Rv1625c membrane-anchored adenylyl cyclase cya   0.37155
Rv1862 alcohol dehydrogenase adhA   0.37031
Rv0050 bifunctional penicillin-binding protein ponA1   0.36996
Rv2752c conserved hypothetical protein   0.36961
Rv3871 conserved hypothetical protein   0.36892
Rv3212 conserved alanine and valine rich protein   0.3678
Rv3433c conserved hypothetical protein   0.36605
Rv2537c 3-dehydroquinate dehydratase aroD   0.36574
Rv2444c ribonuclease E rne   0.3656
Rv2207 nicotinate-nucleotide-dimethylbenzimidazol phosphoribosyltransferase cobT   0.3645
Rv2942 transmembrane transport protein mmpL7   0.36382
Rv1422 conserved hypothetical protein   0.3627
Rv2925c ribonuclease III rnc   0.36071
Rv0724 protease IV sppA   0.36013
Rv2134c conserved hypothetical protein   0.35925
Rv3757c osmoprotectant proW   0.3586
Rv1652 N-acetl-gamma-glutamyl-phoshate reductase argC   0.35842
Rv0811c conserved hypothetical protein   0.3579
Rv2658c phiRv2 phage protein   0.35749
Rv0524 glutamate-1-semialdehyde 2,1-aminomutase hemL   0.35737
Rv2852c malate:quinone oxidoreductase mqo   0.35551
Rv3836 conserved hypothetical protein   0.3555
Rv3068c phosphoglucomutase pgmA   0.35547
Rv1604 inositol-monophosphatase impA   0.35496
Rv2216 conserved hypothetical protein   0.35435
Rv3869 conserved membrane protein   0.35423
Rv2097c conserved hypothetical protein   0.35386
Rv2366c conserved membrane protein   0.35153
Rv1798 conserved hypothetical protein   0.34988
Rv2507 conserved proline rich membrane protein   0.34895
Rv2310 excisionase   0.34849
Rv2325c conserved hypothetical protein   0.34833
Rv1595 L-aspartate oxidase nadB   0.34718
Rv1601 imidazole glycerol-phosphate dehydratase hisB   0.34586
Rv3040c conserved hypothetical protein   0.34505
Rv0245 oxidoreductase   0.34392
Rv1654 acetylglutamate kinase argB   0.3432
Rv2616 conserved hypothetical protein   0.34283
Rv1446c oxpp cycle protein opcA   0.34246
Rv0821c phosphate-transport system transcriptional regulator phoY2   0.34209
Rv3245c two component system sensor histidine kinase mtrB   0.34142
Rv3800c polyketide synthase pks13   0.34126
Rv2995c 3-isopropylmalate dehydrogenase leuB   0.33893
Rv3014c NAD-dependent DNA ligase ligA   0.33858
Rv2210c branched-chain amino acid transaminase ilvE   0.33836
Rv2154c cell division protein ftsW   0.33793
Rv1164 respiratory nitrate reductase gamma chain narI   0.33772
Rv1676 hypothetical protein   0.33687
Rv1104 para-nitrobenzyl esterase   0.33645
Rv1621c transmembrane ATP-binding protein ABC transporter cydD   0.33576
Rv3720 fatty-acid synthase   0.33563
Rv0290 conserved membrane protein   0.33556
Rv3044 Fe(III)-dicitrate-binding periplasmic lipoprotein fecB   0.33526
Rv0659c conserved hypothetical protein   0.33507
Rv2868c 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase gcpE   0.33431
Rv2084 hypothetical protein   0.33403
Rv0676c transmembrane transport protein mmpL5   0.33296
Rv1224 hypothetical protein tatB   0.33286
Rv3038c conserved hypothetical protein   0.33253
Rv1074c beta-ketoacyl CoA thiolase fadA3   0.33233
Rv2753c dihydrodipicolinate synthase dapA   0.332
Rv3816c acyltransferase   0.33088
Rv3605c conserved secreted protein   0.33044
Rv2228c conserved hypothetical protein   0.33022
Rv3264c D-alpha-D-mannose-1-phosphate guanylyltransferase manB   0.33008
Rv1110 lytB-related protein lytB2   0.32985
Rv1512 nucleotide-sugar epimerase epiA   0.32937
Rv3419c O-sialoglycoprotein endopeptidase gcp   0.32863
Rv1796 proline rich membrane-anchored mycosin mycP5   0.32851
Rv0527 cytochrome C biogenesis protein ccdA   0.32779
Rv0342 isoniazid inductible gene protein iniA   0.32728
Rv1634 drug efflux membrane protein   0.32727
Rv1162 respiratory nitrate reductase beta chain narH   0.32704
Rv0015c transmembrane serine/threonine-protein kinase A pknA   0.32646
Rv0590 MCE-family protein mce2B   0.32642
Rv2902c ribonuclease HII protein rnhB   0.32534
Rv1095 phosphate starvation-inducible protein phoH2   0.3253
Rv1478 invasion-associated protein   0.32513
Rv2368c phosphate starvation-inducible protein phoH1   0.32483
Rv1445c 6-phosphogluconolactonase devB   0.32459
Rv0712 conserved hypothetical protein   0.32452
Rv1479 transcriptional regulator moxR1   0.32292
Rv2158c UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelat E ligase murE   0.32054
Rv1338 glutamate racemase murI   0.32047
Rv0514 transmembrane protein   0.31991
Rv1328 glycogen phosphorylase glgP   0.31945
Rv2687c antibiotic-transport membrane leucine and valine rich protein ABC transporter   0.31751
Rv1701 integrase   0.31749
Rv2576c conserved membrane protein   0.3173
Rv0051 conserved membrane protein   0.3168
Rv1415 riboflavin biosynthesis protein ribA2   0.31676
Rv2686c antibiotic-transport membrane leucine and alanine and valine rich protein ABC transporter   0.31616
Rv1334 conserved hypothetical protein   0.31595
Rv3719 conserved hypothetical protein   0.31546
Rv1821 preprotein translocase ATPase secA2   0.31519
Rv2234 phosphotyrosine protein phosphatase ptpA   0.31443
Rv2163c penicillin-binding membrane protein pbpB   0.3137
Rv2164c conserved proline rich membrane protein   0.31296
Rv0525 conserved hypothetical protein   0.3127
Rv1340 ribonuclease rphA   0.31251
Rv0024 secreted protein   0.31233
Rv1072 conserved membrane protein   0.31229
Rv2372c conserved hypothetical protein   0.31223
Rv0512 delta-aminolevulinic acid dehydratase hemB   0.31189
Rv0522 gabA permease gabP   0.31083
Rv0444c conserved hypothetical protein   0.31023
Rv3756c osmoprotectant proZ   0.31004
Rv2217 lipoate biosynthesis protein B lipB   0.31002
Rv2552c shikimate 5-dehydrogenase aroE   0.30993
Rv1448c transaldolase tal   0.30986
Rv0938 ATP dependent DNA ligase   0.30984
Rv3815c acyltransferase   0.30978
Rv1769 conserved hypothetical protein   0.30933
Rv2345 conserved membrane protein   0.30903
Rv0587 hypothetical membrane protein yrbE2A   0.3084
Rv1431 conserved membrane protein   0.30839
Rv0311 hypothetical protein   0.30811
Rv3010c 6-phosphofructokinase pfkA   0.30697
Rv1784 conserved hypothetical protein   0.30696
Rv1841c conserved membrane protein   0.30638
Rv3785 hypothetical protein   0.30604
Rv3694c conserved membrane protein   0.30599
Rv1599 histidinol dehydrogenase hisD   0.30545
Rv2553c conserved membrane protein   0.30542
Rv1600 histidinol-phosphate aminotransferase hisC1   0.30295
Rv1837c malate synthase G glcB   0.30277
Rv0991c conserved serine rich protein   0.30156
Rv3209 conserved proline and threonine rich protein   0.30119
Rv0597c conserved hypothetical protein   0.30093
Rv2471 alpha-glucosidase aglA   0.30064
Rv1223 serine protease htrA   0.30054
Rv1605 cyclase hisF   0.30017