Correlation Catalog M. tuberculosis H37Rv: Rv1603 - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase hisA

Click on the question marks for explanations Hide help
Distribution of gene correlation: Rv1603 vs. all genes ?
COG Categories ?

Information storage and processing

J Translation, ribosomal structure and biogenesis

K Transcription

I DNA replication, recombination and repair

Cellular Processes

D Cell division and chromosome partitioning

O Posttranslational modification, protein turnover, chaperones

M Cell envelope biogenesis, outer membrane

N Cell motility and secretion

P Inorganic transport and metabolism

T Signal transduction mechanisms

Metabolism

C Energy production and conversion

G Carbohydrate transport and metabolism

E Amino acid transport and metabolism

F Nucleotide transport and metabolism

H Coenzyme metabolism

I Lipid metabolism

Q Secondary metabolites biosynthesis, transport and catabolism

Poorly characterized

R General function predicton only

S Unknown function

X No COG assigned

Genes with negative correlation ?

 Categories Enriched ?: None

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv1270c lipoprotein lprA   -0.51509
Rv0739 conserved hypothetical protein   -0.48086
Rv1926c immunogenic protein mpt63   -0.47127
Rv0230c phosphotriesterase php   -0.46875
Rv1876 bacterioferritin bfrA   -0.44343
Rv3390 lipoprotein lpqD   -0.44255
Rv2332 NAD-dependent malate oxidoreductase mez   -0.43701
Rv1740 conserved hypothetical protein   -0.43349
Rv0920c transposase   -0.42989
Rv3890c Esat-6 like protein esxC   -0.41655
Rv0097 oxidoreductase   -0.41289
Rv2638 conserved hypothetical protein   -0.40467
Rv2764c thymidylate synthase thyA   -0.4028
Rv2026c conserved hypothetical protein   -0.40176
Rv0740 conserved hypothetical protein   -0.39875
Rv0268c hypothetical protein   -0.39535
Rv2019 hypothetical protein   -0.39412
Rv0117 oxidative stress response regulatory protein oxyS   -0.39256
Rv0506 membrane protein mmpS2   -0.3921
Rv2020c conserved hypothetical protein   -0.39006
Rv2021c transcriptional regulator   -0.38992
Rv1888c transmembrane protein   -0.38985
Rv1806 PE family protein   -0.38724
Rv2022c conserved hypothetical protein   -0.38633
Rv0456c enoyl-CoA hydratase echA2   -0.3848
Rv1368 lipoprotein lprF   -0.38164
Rv0344c lipoprotein lpqJ   -0.38161
Rv1910c hypothetical exported protein   -0.37914
Rv1535 hypothetical protein   -0.37879
Rv1878 glutamine synthetase glnA3   -0.37783
Rv0942 hypothetical protein   -0.37768
Rv2510c conserved hypothetical protein   -0.37026
Rv0224c methyltransferase/methylase   -0.37004
Rv0030 hypothetical protein   -0.36961
Rv3820c polyketide synthase associated protein papA2   -0.3673
Rv0610c hypothetical protein   -0.36655
Rv1284 conserved hypothetical protein   -0.36517
Rv0322 UDP-glucose 6-dehydrogenase udgA   -0.363
Rv0488 conserved membrane protein   -0.36291
Rv1202 succinyl-diaminopimelate desuccinylase dapE   -0.36203
Rv0730 conserved hypothetical protein   -0.35982
Rv3788 hypothetical protein   -0.35949
Rv3488 conserved hypothetical protein   -0.35814
Rv3789 conserved membrane protein   -0.35806
Rv3642c hypothetical protein   -0.35791
Rv2023c hypothetical protein   -0.35762
Rv0564c glycerol-3-phosphate dehydrogenase gpdA1   -0.35731
Rv0806c UDP-glucose-4-epimerase cpsY   -0.35676
Rv3822 conserved hypothetical protein   -0.35315
Rv1516c sugar transferase   -0.35251
Rv0810c conserved hypothetical protein   -0.35119
Rv0620 galactokinase galK   -0.35083
Rv3172c hypothetical protein   -0.35075
Rv0891c transcriptional regulator   -0.35033
Rv2722 conserved hypothetical protein   -0.34881
Rv1807 PPE family protein   -0.34609
Rv1895 dehydrogenase   -0.34375
Rv1206 fatty-acid-CoA ligase fadD6   -0.34208
Rv2076c hypothetical protein   -0.34063
Rv0854 conserved hypothetical protein   -0.33948
Rv1760 conserved hypothetical protein   -0.33906
Rv2406c conserved hypothetical protein   -0.33861
Rv0825c conserved hypothetical protein   -0.33857
Rv0828c deaminase   -0.33823
Rv0116c conserved membrane protein   -0.33805
Rv2632c conserved hypothetical protein   -0.33633
Rv0948c conserved hypothetical protein   -0.33585
Rv2914c transmembrane serine/threonine-protein kinase I pknI   -0.33561
Rv0150c conserved hypothetical protein   -0.33522
Rv3218 conserved hypothetical protein   -0.33381
Rv0151c PE family protein   -0.3324
Rv2114 hypothetical protein   -0.33226
Rv0924c divalent cation-transport membrane protein mntH   -0.33216
Rv0256c PPE family protein   -0.33159
Rv1254 acyltransferase   -0.32749
Rv1469 cation transporter P-type ATPase D ctpD   -0.32737
Rv2302 conserved hypothetical protein   -0.326
Rv0130 conserved hypothetical protein   -0.32557
Rv3898c conserved hypothetical protein   -0.32332
Rv0088 hypothetical protein   -0.32256
Rv3796 conserved hypothetical protein   -0.32159
Rv2723 conserved membrane protein   -0.32008
Rv1528c polyketide synthase associated protein papA4   -0.31996
Rv2075c hypothetical exported protein   -0.31901
Rv1988 methyltransferase   -0.31765
Rv2416c enhanced intracellular survival protein eis   -0.31762
Rv0566c conserved hypothetical protein   -0.31731
Rv0106 conserved hypothetical protein   -0.31708
Rv2636 conserved hypothetical protein   -0.31552
Rv0872c PE-PGRS family protein   -0.3148
Rv3770c hypothetical leucine rich protein   -0.31428
Rv0008c membrane protein   -0.31371
Rv0033 acyl carrier protein acpA   -0.31287
Rv2253 secreted protein   -0.31112
Rv1646 PE family protein   -0.31066
Rv3750c excisionase   -0.30966
Rv2690c conserved alanine, valine and leucine rich membrane protein   -0.30926
Rv0873 acyl-CoA dehydrogenase fadE10   -0.30897
Rv3633 conserved hypothetical protein   -0.30738
Rv2024c conserved hypothetical protein   -0.30484
Rv3832c conserved hypothetical protein   -0.30473
Rv3736 transcriptional regulator, araC/xylS-family   -0.30445
Rv3891c Esat-6 like protein esxD   -0.30425
Rv0152c PE family protein   -0.30264
Rv0926c conserved hypothetical protein   -0.30155
Rv2742c conserved arginine rich protein   -0.30096

Genes with positive correlation ?

 Categories Enriched ?: H E

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv1601 imidazole glycerol-phosphate dehydratase hisB   0.64952
Rv1602 amidotransferase hisH   0.64728
Rv1605 cyclase hisF   0.63303
Rv1595 L-aspartate oxidase nadB   0.59852
Rv1333 hydrolase   0.59596
Rv2471 alpha-glucosidase aglA   0.56794
Rv2109c proteasome alpha subunit prcA   0.55988
Rv2181 conserved membrane protein   0.55153
Rv1600 histidinol-phosphate aminotransferase hisC1   0.53262
Rv2553c conserved membrane protein   0.52037
Rv2365c conserved hypothetical protein   0.51656
Rv1596 nicotinate-nucleotide pyrophosphatase nadC   0.51351
Rv2537c 3-dehydroquinate dehydratase aroD   0.50921
Rv0528 conserved membrane protein   0.5072
Rv1837c malate synthase G glcB   0.50598
Rv1797 conserved hypothetical protein   0.50461
Rv2367c hypothetical protein   0.50004
Rv1599 histidinol dehydrogenase hisD   0.49688
Rv0015c transmembrane serine/threonine-protein kinase A pknA   0.49684
Rv1421 conserved hypothetical protein   0.48879
Rv2678c uroporphyrinogen decarboxylase hemE   0.48849
Rv3877 conserved membrane protein   0.48489
Rv3256c conserved hypothetical protein   0.48307
Rv0613c hypothetical protein   0.4766
Rv0511 uroporphyrin-III C-methyltransferase hemD   0.47586
Rv0710 30S ribosomal protein S17 rpsQ   0.47495
Rv3871 conserved hypothetical protein   0.4725
Rv1539 lipoprotein signal peptidase lspA   0.47163
Rv3419c O-sialoglycoprotein endopeptidase gcp   0.47101
Rv1594 quinolinate synthetase nadA   0.47098
Rv2936 daunorubicin-dim-transport ATP-binding protein ABC transporter drrA   0.46957
Rv3858c NADH-dependent glutamate synthase small subunit gltD   0.4686
Rv1100 conserved hypothetical protein   0.46184
Rv2444c ribonuclease E rne   0.45855
Rv2131c monophosphatase cysQ   0.45623
Rv1411c lipoprotein lprG   0.45613
Rv1121 glucose-6-phosphate 1-dehydrogenase zwf1   0.45331
Rv2611c acyltransferase   0.45222
Rv3859c ferredoxin-dependent glutamate synthase large subunit gltB   0.44862
Rv1540 conserved hypothetical protein   0.4483
Rv1483 3-oxoacyl-[acyl-carrier protein] reductase fabG1   0.44802
Rv0472c transcriptional regulator, tetR-family   0.44778
Rv3551 CoA-transferase alpha subunit   0.44754
Rv1173 F420 biosynthesis protein fbiC   0.44659
Rv2613c conserved hypothetical protein   0.44392
Rv1007c methionyl-tRNA synthetase metS   0.44375
Rv0513 conserved membrane protein   0.44263
Rv3626c conserved hypothetical protein   0.4397
Rv1301 conserved hypothetical protein   0.43427
Rv1597 hypothetical protein   0.43266
Rv2197c conserved membrane protein   0.4326
Rv3813c conserved hypothetical protein   0.43002
Rv0411c glutamine-binding lipoprotein glnH   0.42842
Rv3212 conserved alanine and valine rich protein   0.4271
Rv2539c shikimate kinase aroK   0.42705
Rv1836c conserved hypothetical protein   0.42679
Rv2207 nicotinate-nucleotide-dimethylbenzimidazol phosphoribosyltransferase cobT   0.42639
Rv0721 30S ribosomal protein S5 rpsE   0.42591
Rv3003c acetolactate synthase large subunit ilvB1   0.42458
Rv2942 transmembrane transport protein mmpL7   0.4242
Rv3284 conserved hypothetical protein   0.42414
Rv1565c conserved membrane protein   0.42251
Rv1449c transketolase tkt   0.42164
Rv1415 riboflavin biosynthesis protein ribA2   0.42057
Rv1294 homoserine dehydrogenase thrA   0.42047
Rv2368c phosphate starvation-inducible protein phoH1   0.42028
Rv1309 ATP synthase gamma chain atpG   0.42012
Rv0809 phosphoribosylformylglycinamidine cyclo-ligase purM   0.41964
Rv2151c cell division protein ftsQ   0.4195
Rv0975c acyl-CoA dehydrogenase fadE13   0.41908
Rv1606 phosphoribosyl-AMP-1,6-cyclohydrolase hisI   0.41553
Rv2195 Rieske iron-sulfur protein qcrA   0.41506
Rv2933 phenolpthiocerol synthesis type-I polyketide synthase ppsC   0.41438
Rv2589 4-aminobutyrate aminotransferase gabT   0.41002
Rv3002c acetolactate synthase small subunit ilvN   0.40948
Rv0615 membrane protein   0.4083
Rv1165 GTP-binding translation elongation factor typA   0.40604
Rv3149 NADH dehydrogenase I chain E nuoE   0.40597
Rv0931c transmembrane serine/threonine-protein kinase D pknD   0.40583
Rv0865 molybdopterin biosynthesis protein mog   0.40386
Rv1383 carbamoyl-phosphate synthase small chain carA   0.40262
Rv1381 dihydroorotase pyrC   0.40142
Rv3627c conserved hypothetical protein   0.40077
Rv0722 50S ribosomal protein L30 rpmD   0.40036
Rv2932 phenolpthiocerol synthesis type-I polyketide synthase ppsB   0.39647
Rv3870 conserved membrane protein   0.39542
Rv1416 riboflavin synthase beta chain ribH   0.39535
Rv2335 serine acetyltransferase cysE   0.39481
Rv3422c conserved hypothetical protein   0.39479
Rv3869 conserved membrane protein   0.39459
Rv0491 two component system sensor protein regX3   0.39389
Rv2345 conserved membrane protein   0.39375
Rv1925 acyl-CoA ligase fadD31   0.39335
Rv3608c dihydropteroate synthase 1 folp   0.39329
Rv1324 thioredoxin   0.39316
Rv0299 hypothetical protein   0.39238
Rv2703 RNA polymerase sigma factor sigA   0.39032
Rv0875c hypothetical exported protein   0.38933
Rv1391 DNA/pantothenate metabolism flavoprotein dfp   0.38474
Rv3370c DNA polymerase III alpha chain dnaE2   0.38441
Rv2196 ubiquinol-cytochrome C reductase qcrB cytochrome B subunit   0.38176
Rv3805c conserved membrane protein   0.38114
Rv0247c succinate dehydrogenase iron-sulfur subunit   0.38095
Rv0383c conserved secreted protein   0.38023
Rv1223 serine protease htrA   0.38003
Rv3609c GTP cyclohydrolase I folE   0.37887
Rv3285 bifunctional acetyl-/propionyl-coenzyme A carboxylase alpha chain accA3   0.37852
Rv3835 conserved membrane protein   0.37814
Rv0410c serine/threonine-protein kinase pknG   0.37759
Rv3550 enoyl-CoA hydratase echA20   0.37713
Rv1310 ATP synthase beta chain atpD   0.3764
Rv0509 glutamyl-tRNA reductase hemA   0.37623
Rv3433c conserved hypothetical protein   0.37578
Rv0014c transmembrane serine/threonine-protein kinase B pknB   0.37524
Rv2327 conserved hypothetical protein   0.37471
Rv3799c propionyl-CoA carboxylase beta chain 4 accD4   0.37329
Rv3757c osmoprotectant proW   0.37311
Rv3607c dihydroneopterin aldolase folB   0.37207
Rv3339c isocitrate dehydrogenase icd1   0.372
Rv2326c transmembrane ATP-binding protein ABC transorter   0.37123
Rv2753c dihydrodipicolinate synthase dapA   0.36943
Rv0486 mannosyltransferase   0.36873
Rv1209 conserved hypothetical protein   0.36853
Rv0421c conserved hypothetical protein   0.36829
Rv2848c cobyrinic acid a,c-diamide synthase cobB   0.36787
Rv3421c conserved hypothetical protein   0.36749
Rv2859c amidotransferase   0.36679
Rv0018c serine/threonine phosphatase ppp   0.36619
Rv1701 integrase   0.36611
Rv0365c conserved hypothetical protein   0.36361
Rv3255c mannose-6-phosphate isomerase manA   0.36216
Rv1003 conserved hypothetical protein   0.36196
Rv0512 delta-aminolevulinic acid dehydratase hemB   0.36192
Rv3151 NADH dehydrogenase I chain G nuoG   0.36185
Rv1583c phiRv1 phage protein   0.36163
Rv2117 conserved hypothetical protein   0.36131
Rv2417c conserved hypothetical protein   0.3608
Rv2605c acyl-CoA thioesterase II tesB2   0.35926
Rv0005 DNA gyrase subunit B gyrB   0.35864
Rv1410c aminoglycosides/tetracycline-transport membrane protein   0.35826
Rv2325c conserved hypothetical protein   0.35808
Rv0972c acyl-CoA dehydrogenase fadE12   0.3573
Rv3856c conserved hypothetical protein   0.35706
Rv0463 conserved membrane protein   0.35672
Rv1479 transcriptional regulator moxR1   0.35594
Rv3157 NADH dehydrogenase I chain M nuoM   0.35558
Rv2130c cysteinyl-tRNA synthetase 2 cysS2   0.35533
Rv1655 acetylornithine aminotransferase argD   0.35462
Rv2923c conserved hypothetical protein   0.35433
Rv0285 PE family protein   0.35268
Rv3140 acyl-CoA dehydrogenase fadE23   0.35259
Rv2885c transposase   0.35204
Rv1576c phiRv1 phage protein   0.35097
Rv3019c Esat-6 like protein esxR   0.35084
Rv3552 CoA-transferase beta subunit   0.35065
Rv2905 alanine rich lipoprotein lppW   0.34945
Rv1083 conserved hypothetical protein   0.34921
Rv1295 threonine synthase thrC   0.34894
Rv2587c protein-export membrane protein secD   0.34792
Rv3541c conserved hypothetical protein   0.3465
Rv3800c polyketide synthase pks13   0.34648
Rv0973c acetyl-/propionyl-CoA carboxylase alpha subunit accA2   0.34624
Rv0659c conserved hypothetical protein   0.34477
Rv0525 conserved hypothetical protein   0.34407
Rv1311 ATP synthase epsilon chain atpC   0.34368
Rv3297 endonuclease VIII nei   0.34351
Rv2554c conserved hypothetical protein   0.34328
Rv1297 transcription termination factor rho   0.34307
Rv2538c 3-dehydroquinate synthase aroB   0.3426
Rv1097c glycine and proline rich membrane protein   0.34163
Rv3336c tryptophanyl-tRNA synthetase trpS   0.34136
Rv3703c conserved hypothetical protein   0.34125
Rv3093c oxidoreductase   0.34065
Rv3028c electron transfer flavoprotein alpha subunit fixB   0.34047
Rv2551c conserved hypothetical protein   0.34034
Rv1323 acetyl-CoA acetyltransferase fadA4   0.33866
Rv2931 phenolpthiocerol synthesis type-I polyketide synthase ppsA   0.33833
Rv1224 hypothetical protein tatB   0.33817
Rv1300 hypothetical protein hemK   0.33816
Rv2133c conserved hypothetical protein   0.33769
Rv2470 oxygen-binding protein globin glbO   0.33718
Rv2925c ribonuclease III rnc   0.33628
Rv1593c conserved hypothetical protein   0.33622
Rv1328 glycogen phosphorylase glgP   0.33619
Rv3244c lipoprotein lpqB   0.33443
Rv0289 conserved hypothetical protein   0.33364
Rv1315 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA   0.33334
Rv3411c inosine-5-monophosphate dehydrogenase guaB2   0.33284
Rv2039c sugar-transport membrane protein ABC transporter   0.33281
Rv1784 conserved hypothetical protein   0.33101
Rv1635c conserved membrane protein   0.33073
Rv3807c conserved membrane protein   0.33033
Rv2372c conserved hypothetical protein   0.32937
Rv1417 conserved membrane protein   0.32909
Rv1627c nonspecific lipid-transfer protein   0.32897
Rv0412c conserved membrane protein   0.32875
Rv2164c conserved proline rich membrane protein   0.32863
Rv0709 50S ribosomal protein L29 rpmC   0.32835
Rv1982c conserved hypothetical protein   0.32816
Rv1578c phiRv1 phage protein   0.32777
Rv0049 conserved hypothetical protein   0.32763
Rv3257c phosphomannomutase pmmA   0.32757
Rv3605c conserved secreted protein   0.32753
Rv1445c 6-phosphogluconolactonase devB   0.3274
Rv1615 hypothetical membrane protein   0.32655
Rv2938 daunorubicin-dim-transport membrane protein ABC transporter drrC   0.32572
Rv2509 short-chain type dehydrogenase/reductase   0.32529
Rv0864 molybdenum cofactor biosynthesis protein C 2 moaC2   0.32518
Rv2373c chaperone protein dnaJ2   0.32497
Rv2393 conserved hypothetical protein   0.32445
Rv2477c macrolide-transport ATP-binding protein ABC transporter   0.32422
Rv3283 thiosulfate sulfurtransferase sseA   0.32338
Rv3563 acyl-CoA dehydrogenase fadE32   0.32323
Rv1025 conserved hypothetical protein   0.32318
Rv0587 hypothetical membrane protein yrbE2A   0.32232
Rv1337 membrane protein   0.32206
Rv0315 beta-1,3-glucanase precursor   0.32152
Rv1289 hypothetical protein   0.32145
Rv2939 polyketide synthase associated protein papA5   0.32027
Rv2503c succinyl-CoA:3-ketoacid-coenzyme A transferase beta subunit scoB   0.31997
Rv3001c ketol-acid reductoisomerase ilvC   0.31906
Rv2851c conserved hypothetical protein   0.31897
Rv1845c conserved membrane protein   0.31886
Rv1939 oxidoreductase   0.31786
Rv1495 conserved hypothetical protein   0.31745
Rv2134c conserved hypothetical protein   0.31743
Rv1332 transcriptional regulator   0.3174
Rv2064 cobalamin biosynthesis protein cobG   0.31732
Rv1451 cytochrome C oxidase assembly factor ctaB   0.31665
Rv2153c UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase murG   0.31574
Rv3281 conserved hypothetical protein   0.31523
Rv2782c zinc protease pepR   0.31493
Rv1308 ATP synthase alpha chain atpA   0.31463
Rv0245 oxidoreductase   0.31413
Rv2883c uridylate kinase pyrH   0.31331
Rv3145 NADH dehydrogenase I chain A nuoA   0.3131
Rv3245c two component system sensor histidine kinase mtrB   0.31225
Rv0495c conserved hypothetical protein   0.31163
Rv0050 bifunctional penicillin-binding protein ponA1   0.31154
Rv3137 monophosphatase   0.31132
Rv2499c oxidase regulatory-related protein   0.31014
Rv0283 conserved membrane protein   0.31006
Rv1101c conserved membrane protein   0.31005
Rv2583c GTP pyrophosphokinase relA   0.30918
Rv2125 conserved hypothetical protein   0.30887
Rv2752c conserved hypothetical protein   0.30882
Rv1233c conserved membrane protein   0.30794
Rv2447c folylpolyglutamate synthase protein folC   0.30776
Rv2995c 3-isopropylmalate dehydrogenase leuB   0.30763
Rv2881c membrane phosphatidate cytidylyltransferase cdsA   0.30725
Rv1480 conserved hypothetical protein   0.30707
Rv1437 phosphoglycerate kinase pgk   0.30629
Rv1751 oxidoreductase   0.30532
Rv3879c hypothetical alanine and proline rich protein   0.30486
Rv1843c inosine-5-monophosphate dehydrogenase guaB1   0.30448
Rv1341 conserved hypothetical protein   0.30446
Rv1340 ribonuclease rphA   0.30385
Rv0290 conserved membrane protein   0.30344
Rv0818 transcriptional regulator   0.30341
Rv3709c aspartokinase ask   0.30287
Rv2540c chorismate synthase aroF   0.30267
Rv3030 conserved hypothetical protein   0.30196
Rv2234 phosphotyrosine protein phosphatase ptpA   0.30126
Rv1110 lytB-related protein lytB2   0.30108
Rv0526 thioredoxin   0.30097
Rv2869c conserved membrane protein   0.3006
Rv1217c tetronasin-transport membrane protein ABC transporter   0.30031