Correlation Catalog M. tuberculosis H37Rv: Rv2216 - conserved hypothetical protein

Click on the question marks for explanations Hide help
Distribution of gene correlation: Rv2216 vs. all genes ?
COG Categories ?

Information storage and processing

J Translation, ribosomal structure and biogenesis

K Transcription

I DNA replication, recombination and repair

Cellular Processes

D Cell division and chromosome partitioning

O Posttranslational modification, protein turnover, chaperones

M Cell envelope biogenesis, outer membrane

N Cell motility and secretion

P Inorganic transport and metabolism

T Signal transduction mechanisms

Metabolism

C Energy production and conversion

G Carbohydrate transport and metabolism

E Amino acid transport and metabolism

F Nucleotide transport and metabolism

H Coenzyme metabolism

I Lipid metabolism

Q Secondary metabolites biosynthesis, transport and catabolism

Poorly characterized

R General function predicton only

S Unknown function

X No COG assigned

Genes with negative correlation ?

 Categories Enriched ?: None

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv2255c hypothetical protein   -0.48694
Rv2663 hypothetical protein   -0.48245
Rv2022c conserved hypothetical protein   -0.44552
Rv2714 conserved alanine and leucine rich protein   -0.44427
Rv0471c hypothetical protein   -0.43127
Rv1990c transcriptional regulator   -0.4266
Rv1239c magnesium and cobalt transport transmembrane protein corA   -0.42607
Rv2021c transcriptional regulator   -0.41734
Rv1365c anti-anti-sigma factor rsfA   -0.41015
Rv2177c transposase   -0.40867
Rv3183 transcriptional regulator   -0.40854
Rv1660 chalcone synthase pks10   -0.40715
Rv3521 conserved hypothetical protein   -0.40552
Rv0137c peptide methionine sulfoxide reductase msrA   -0.40417
Rv2034 arsR-type repressor protein   -0.4036
Rv2961 transposase   -0.40128
Rv2341 lipoprotein lppQ   -0.39762
Rv0305c PPE family protein   -0.39549
Rv2254c membrane protein   -0.39467
Rv0873 acyl-CoA dehydrogenase fadE10   -0.38833
Rv2306c   -0.38758
Rv3357 conserved hypothetical protein   -0.38492
Rv1986 conserved membrane protein   -0.38427
Rv2493 conserved hypothetical protein   -0.38411
Rv2175c conserved hypothetical protein   -0.38233
Rv0767c conserved hypothetical protein   -0.38169
Rv1750c fatty-acid-CoA ligase fadD1   -0.38161
Rv3425 PPE family protein   -0.38001
Rv0885 conserved hypothetical protein   -0.37588
Rv1284 conserved hypothetical protein   -0.3744
Rv1044 conserved hypothetical protein   -0.37396
Rv2661c hypothetical protein   -0.37034
Rv3862c transcriptional regulator whiB-like whiB6   -0.37024
Rv2107 PE family protein   -0.36986
Rv1955 hypothetical protein   -0.36523
Rv0232 transcriptional regulator, tetR/acrR-family   -0.36466
Rv0264c conserved hypothetical protein   -0.36309
Rv2016 hypothetical protein   -0.36225
Rv1169c PE family protein   -0.36078
Rv0331 dehydrogenase/reductase   -0.3582
Rv0027 hypothetical protein   -0.35654
Rv3016 lipoprotein lpqA   -0.35582
Rv0112 GDP-mannose 4,6-dehydratase gca   -0.35194
Rv3337 conserved hypothetical protein   -0.34971
Rv3340 O-acetylhomoserine sulfhydrylase metC   -0.34881
Rv1356c hypothetical protein   -0.34749
Rv3832c conserved hypothetical protein   -0.34738
Rv1628c conserved hypothetical protein   -0.34737
Rv1439c hypothetical protein   -0.34698
Rv0689c hypothetical protein   -0.34648
Rv0624 conserved hypothetical protein   -0.34604
Rv1804c conserved hypothetical protein   -0.34518
Rv2779c transcriptional regulator, lrp/asnC-family   -0.3443
Rv0840c proline iminopeptidase pip   -0.34268
Rv3334 transcriptional regulator, merR-family   -0.34204
Rv2132 conserved hypothetical protein   -0.34104
Rv1221 alternative RNA polymerase sigma factor sigE   -0.341
Rv3650 PE family protein   -0.34071
Rv1015c 50S ribosomal protein L25 rplY   -0.33986
Rv1056 conserved hypothetical protein   -0.33881
Rv2664 hypothetical protein   -0.3386
Rv0277c conserved hypothetical protein   -0.33786
Rv2371 PE-PGRS family protein   -0.33658
Rv3903c hypothetical alanine and proline rich protein   -0.33626
Rv1960c conserved hypothetical protein   -0.33488
Rv0122 hypothetical protein   -0.33467
Rv0520 methyltransferase/methylase   -0.33291
Rv0648 alpha-mannosidase   -0.33239
Rv1432 dehydrogenase   -0.33227
Rv3371 conserved hypothetical protein   -0.33142
Rv2777c conserved hypothetical protein   -0.33126
Rv2056c 30S ribosomal protein S14 rpsN2   -0.33038
Rv3180c hypothetical alanine rich protein   -0.33008
Rv2323c conserved hypothetical protein   -0.32986
Rv3007c oxidoreductase   -0.32906
Rv2662 hypothetical protein   -0.32856
Rv3391 acyl-CoA reductase acrA1   -0.32776
Rv1989c hypothetical protein   -0.32757
Rv2035 conserved hypothetical protein   -0.32686
Rv1806 PE family protein   -0.32638
Rv3891c Esat-6 like protein esxD   -0.32486
Rv1951c conserved hypothetical protein   -0.32427
Rv2660c hypothetical protein   -0.32346
Rv1057 conserved hypothetical protein   -0.32329
Rv2827c hypothetical protein   -0.32219
Rv3651 conserved hypothetical protein   -0.32063
Rv3383c polyprenyl synthetase idsB   -0.32047
Rv3115 transposase   -0.31969
Rv3736 transcriptional regulator, araC/xylS-family   -0.31774
Rv1052 hypothetical protein   -0.31726
Rv0008c membrane protein   -0.31706
Rv2878c soluble secreted antigen mpt53 precursor   -0.31656
Rv2324 transcriptional regulator, asnC-family   -0.3165
Rv3123 hypothetical protein   -0.31644
Rv0330c hypothetical protein   -0.31606
Rv2813 conserved hypothetical protein   -0.31601
Rv3526 oxidoreductase   -0.31545
Rv0750 conserved hypothetical protein   -0.31526
Rv2667 ATP-dependent protease ATP-binding subunit clpC2   -0.31522
Rv0230c phosphotriesterase php   -0.3151
Rv0612 conserved hypothetical protein   -0.3148
Rv0887c conserved hypothetical protein   -0.31358
Rv0089 methyltransferase/methylase   -0.31316
Rv2295 conserved hypothetical protein   -0.31274
Rv3749c conserved hypothetical protein   -0.31219
Rv3235 hypothetical alanine, arginine and proline rich protein   -0.31163
Rv3898c conserved hypothetical protein   -0.31153
Rv1791 PE family protein   -0.31061
Rv3488 conserved hypothetical protein   -0.31032
Rv0571c conserved hypothetical protein   -0.30909
Rv1724c hypothetical protein   -0.30903
Rv1774 oxidoreductase   -0.30795
Rv1187 pyrroline-5-carboxylate dehydrogenase rocA   -0.30777
Rv1150 transposase   -0.30736
Rv2666 transposase   -0.3071
Rv0807 conserved hypothetical protein   -0.30691
Rv0263c conserved hypothetical protein   -0.30691
Rv2353c PPE family protein   -0.30642
Rv3517 conserved hypothetical protein   -0.30632
Rv0657c conserved hypothetical protein   -0.30628
Rv2424c transposase   -0.30545
Rv0739 conserved hypothetical protein   -0.30502
Rv3416 transcriptional regulator whib-like whiB3   -0.30372
Rv0595c conserved hypothetical protein   -0.30372
Rv2641 cadmium inducible protein cadI   -0.30349
Rv2266 cytochrome P450 124 cyp124   -0.30164
Rv1247c conserved hypothetical protein   -0.30112
Rv2656c phiRv2 phage protein   -0.30042
Rv3182 conserved hypothetical protein   -0.30024
Rv1581c phiRv1 phage protein   -0.3001

Genes with positive correlation ?

 Categories Enriched ?: C

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv2214c short-chain type dehydrogenase ephD   0.56159
Rv3708c aspartate-semialdehyde dehydrogenase asd   0.54487
Rv0527 cytochrome C biogenesis protein ccdA   0.54479
Rv1438 triosephosphate isomerase tpi   0.52311
Rv0444c conserved hypothetical protein   0.51064
Rv0058 replicative DNA helicase dnaB   0.48904
Rv1446c oxpp cycle protein opcA   0.48766
Rv1448c transaldolase tal   0.47833
Rv3148 NADH dehydrogenase I chain D nuoD   0.47152
Rv3678c conserved hypothetical protein   0.46699
Rv2604c conserved hypothetical protein   0.46605
Rv1679 acyl-CoA dehydrogenase fadE16   0.45735
Rv1306 ATP synthase B chain atpF   0.45425
Rv2238c peroxiredoxin ahpE   0.4514
Rv0734 methionine aminopeptidase mapA   0.44934
Rv1427c long-chain fatty-acid-CoA ligase fadD12   0.44804
Rv2196 ubiquinol-cytochrome C reductase qcrB cytochrome B subunit   0.44705
Rv1133c 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase metE   0.44323
Rv0528 conserved membrane protein   0.44001
Rv0014c transmembrane serine/threonine-protein kinase B pknB   0.43973
Rv2732c conserved membrane protein   0.43779
Rv0931c transmembrane serine/threonine-protein kinase D pknD   0.43379
Rv3200c transmembrane cation transporter   0.43174
Rv2195 Rieske iron-sulfur protein qcrA   0.43167
Rv3264c D-alpha-D-mannose-1-phosphate guanylyltransferase manB   0.42894
Rv0896 citrate synthase I gltA2   0.42784
Rv2074 conserved hypothetical protein   0.42676
Rv2524c fatty-acid synthase fas   0.42503
Rv2334 cysteine synthase A cysK1   0.42355
Rv1240 malate dehydrogenase mdh   0.42216
Rv2230c conserved hypothetical protein   0.42184
Rv2883c uridylate kinase pyrH   0.42116
Rv1307 ATP synthase delta chain atpH   0.4173
Rv2475c conserved hypothetical protein   0.41692
Rv1477 invasion-associated protein   0.41632
Rv1751 oxidoreductase   0.41604
Rv3800c polyketide synthase pks13   0.41539
Rv1606 phosphoribosyl-AMP-1,6-cyclohydrolase hisI   0.41516
Rv0220 esterase lipC   0.41465
Rv2231c aminotransferase cobC   0.4137
Rv2215 pyruvate dehydrogenase E2 component sucB   0.41233
Rv2882c ribosome recycling factor frr   0.41027
Rv1328 glycogen phosphorylase glgP   0.40894
Rv3156 NADH dehydrogenase I chain L nuoL   0.40886
Rv2881c membrane phosphatidate cytidylyltransferase cdsA   0.40819
Rv2476c NAD-dependent glutamate dehydrogenase gdh   0.40664
Rv3564 acyl-CoA dehydrogenase fadE33   0.40518
Rv3799c propionyl-CoA carboxylase beta chain 4 accD4   0.40503
Rv2593c holliday junction DNA helicase ruvA   0.40407
Rv3146 NADH dehydrogenase I chain B nuoB   0.40194
Rv1311 ATP synthase epsilon chain atpC   0.4006
Rv1610 conserved membrane protein   0.39998
Rv3154 NADH dehydrogenase I chain J nuoJ   0.39941
Rv0168 hypothetical membrane protein yrbE1B   0.39904
Rv3151 NADH dehydrogenase I chain G nuoG   0.39703
Rv0050 bifunctional penicillin-binding protein ponA1   0.39656
Rv3774 enoyl-CoA hydratase echA21   0.39638
Rv1162 respiratory nitrate reductase beta chain narH   0.39479
Rv2468c conserved hypothetical protein   0.39236
Rv3303c dihydrolipoamide dehydrogenase lpdA   0.39088
Rv0036c conserved hypothetical protein   0.39058
Rv1233c conserved membrane protein   0.38917
Rv0733 adenylate kinase adk   0.38916
Rv2477c macrolide-transport ATP-binding protein ABC transporter   0.38913
Rv2572c aspartyl-tRNA synthetase aspS   0.38798
Rv3153 NADH dehydrogenase I chain I nuoI   0.38788
Rv2054 conserved hypothetical protein   0.38786
Rv0890c transcriptional regulator, luxR-family   0.3873
Rv1007c methionyl-tRNA synthetase metS   0.38648
Rv2192c anthranilate phosphoribosyltransferase trpD   0.38644
Rv0222 enoyl-CoA hydratase echA1   0.3857
Rv3158 NADH dehydrogenase I chain N nuoN   0.38565
Rv2210c branched-chain amino acid transaminase ilvE   0.38561
Rv1107c exodeoxyribonuclease VII small subunit xseB   0.3854
Rv0200 conserved membrane protein   0.38376
Rv1173 F420 biosynthesis protein fbiC   0.38357
Rv3494c MCE-family protein mce4F   0.38349
Rv2752c conserved hypothetical protein   0.38204
Rv1614 prolipoprotein diacylglyceryl transferases lgt   0.38171
Rv3783 O-antigen/lipopolysaccharide transport membrane protein ABC transporter rfbD   0.38135
Rv0103c cation-transporter P-type ATPase B ctpB   0.3799
Rv3419c O-sialoglycoprotein endopeptidase gcp   0.3792
Rv3496c MCE-family protein mce4D   0.37904
Rv1445c 6-phosphogluconolactonase devB   0.37676
Rv2139 dihydroorotate dehydrogenase pyrD   0.37409
Rv1613 tryptophan synthase, alpha subunit trpA   0.37367
Rv3480c conserved hypothetical protein   0.37258
Rv1437 phosphoglycerate kinase pgk   0.37191
Rv3150 NADH dehydrogenase I chain F nuoF   0.37154
Rv2219 conserved membrane protein   0.37113
Rv1480 conserved hypothetical protein   0.3696
Rv1932 thiol peroxidase tpx   0.3694
Rv1908c catalase-peroxidase-peroxynitritase T katG   0.3692
Rv1596 nicotinate-nucleotide pyrophosphatase nadC   0.36829
Rv1304 ATP synthase A chain atpB   0.36604
Rv1836c conserved hypothetical protein   0.36537
Rv1098c fumarase fum   0.36507
Rv1309 ATP synthase gamma chain atpG   0.36489
Rv1426c esterase lipO   0.36459
Rv2574 conserved hypothetical protein   0.36436
Rv3806c conserved membrane protein   0.36418
Rv1220c methyltransferase   0.36391
Rv3420c ribosomal-protein-alanine acetyltransferase rimI   0.36333
Rv1070c enoyl-CoA hydratase echA8   0.36321
Rv1422 conserved hypothetical protein   0.362
Rv2228c conserved hypothetical protein   0.3618
Rv3626c conserved hypothetical protein   0.36174
Rv1590 conserved hypothetical protein   0.36173
Rv0491 two component system sensor protein regX3   0.36081
Rv1770 conserved hypothetical protein   0.36031
Rv2207 nicotinate-nucleotide-dimethylbenzimidazol phosphoribosyltransferase cobT   0.35952
Rv1634 drug efflux membrane protein   0.35943
Rv1166 lipoprotein lpqW   0.35927
Rv0935 phosphate-transport membrane ABC transporter pstC1   0.35851
Rv2152c UDP-N-acetylmuramate-alanine ligase murC   0.3585
Rv3042c phosphoserine phosphatase serB2   0.35759
Rv0418 lipoprotein aminopeptidase lpqL   0.35731
Rv3255c mannose-6-phosphate isomerase manA   0.3563
Rv2992c glutamyl-tRNA synthetase gltS   0.35611
Rv1310 ATP synthase beta chain atpD   0.3561
Rv1324 thioredoxin   0.35596
Rv0462 dihydrolipoamide dehydrogenase lpd   0.35509
Rv1547 DNA polymerase III alpha chain dnaE1   0.3544
Rv2678c uroporphyrinogen decarboxylase hemE   0.35435
Rv2217 lipoate biosynthesis protein B lipB   0.35365
Rv3498c MCE-family protein mce4B   0.35326
Rv1449c transketolase tkt   0.35229
Rv2791c transposase   0.35163
Rv2770c PPE family protein   0.35155
Rv3282 conserved hypothetical protein   0.35135
Rv2794c conserved hypothetical protein   0.35108
Rv3075c conserved hypothetical protein   0.35041
Rv2260 conserved hypothetical protein   0.3501
Rv0337c aspartate aminotransferase aspC   0.34989
Rv2610c alpha-mannosyltransferase pimA   0.34952
Rv2446c conserved membrane protein   0.34919
Rv1447c glucose-6-phosphate 1-dehydrogenase zwf2   0.34909
Rv0554 non-haem peroxidase bpoC   0.34897
Rv1695 inorganic polyphosphate/ATP-NAD kinase ppnK   0.34879
Rv1305 ATP synthase C chain atpE   0.34764
Rv1308 ATP synthase alpha chain atpA   0.34739
Rv1612 tryptophan synthase, beta subunit trpB   0.34719
Rv2314c conserved hypothetical protein   0.34676
Rv3275c phosphoribosylaminoimidazole carboxylase catalytic subunit purE   0.3462
Rv2782c zinc protease pepR   0.34612
Rv2350c membrane-associated phospholipase C 2 plcB   0.34591
Rv2198c membrane protein mmpS3   0.34513
Rv2680 conserved hypothetical protein   0.34505
Rv1618 acyl-CoA thioesterase II tesB1   0.34503
Rv2206 conserved membrane protein   0.34425
Rv2127 L-asparagine permease ansP1   0.34413
Rv0907 conserved hypothetical protein   0.34305
Rv1713 GTP-binding protein engA   0.34249
Rv1676 hypothetical protein   0.34224
Rv3330 penicillin-binding protein dacB1   0.34187
Rv2148c conserved hypothetical protein   0.34032
Rv0171 MCE-family protein mce1C   0.33989
Rv0526 thioredoxin   0.33984
Rv2796c lipoprotein lppV   0.33862
Rv1544 ketoacyl reductase   0.33831
Rv2110c proteasome beta subunit prcB   0.33803
Rv1121 glucose-6-phosphate 1-dehydrogenase zwf1   0.33796
Rv3680 anion transporter ATPase   0.33757
Rv3149 NADH dehydrogenase I chain E nuoE   0.33678
Rv0820 phosphate-transport ATP-binding protein ABC transporter phoT   0.33641
Rv1540 conserved hypothetical protein   0.33616
Rv0176 MCE-associated transmembrane protein   0.33577
Rv0170 MCE-family protein mce1B   0.33573
Rv0248c succinate dehydrogenase iron-sulfur subunit   0.33553
Rv1595 L-aspartate oxidase nadB   0.33529
Rv1436 glyceraldehyde 3-phosphate dehydrogenase gap   0.3348
Rv3624c hypoxanthine-guanine phosphoribosyltransferase hpt   0.33455
Rv2594c crossover junction endodeoxyribonuclease ruvC   0.33289
Rv1906c conserved hypothetical protein   0.33275
Rv2845c prolyl-tRNA synthetase proS   0.33261
Rv0010c conserved membrane protein   0.33245
Rv3152 NADH dehydrogenase I chain H nuoH   0.33176
Rv3045 NADP-dependent alcohol dehydrogenase adhC   0.33156
Rv3417c 60 kda chaperonin 1 groEL1   0.33125
Rv1611 indole-3-glycerol phosphate synthase trpC   0.33122
Rv0346c L-asparagine permease ansP2   0.33111
Rv1387 PPE family protein   0.33
Rv1631 dephospho-CoA kinase coaE   0.32993
Rv1303 conserved membrane protein   0.32807
Rv2674 conserved hypothetical protein   0.32783
Rv2836c DNA-damage-inducible protein F dinF   0.32653
Rv1650 phenylalanyl-tRNA synthetase beta chain pheT   0.32596
Rv0760c conserved hypothetical protein   0.3254
Rv0018c serine/threonine phosphatase ppp   0.32513
Rv2552c shikimate 5-dehydrogenase aroE   0.32427
Rv2855 NADPH-dependent mycothiol reductase mtr   0.32372
Rv3587c conserved membrane protein   0.32361
Rv0006 DNA gyrase subunit A gyrA   0.32352
Rv2280 dehydrogenase   0.32342
Rv0177 MCE-associated protein   0.32306
Rv2900c formate dehydrogenase H fdhF   0.32241
Rv3335c conserved membrane protein   0.32239
Rv3040c conserved hypothetical protein   0.32198
Rv3410c inosine-5-monophosphate dehydrogenase guaB3   0.32198
Rv2474c conserved hypothetical protein   0.32159
Rv1677 lipoprotein dsbF   0.32131
Rv1694 cytotoxin|haemolysin tlyA   0.32063
Rv2448c valyl-tRNA synthase protein valS   0.31989
Rv3606c 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK   0.31983
Rv0174 MCE-family protein mce1F   0.31982
Rv3608c dihydropteroate synthase 1 folp   0.31955
Rv1069c conserved hypothetical protein   0.31911
Rv1602 amidotransferase hisH   0.31873
Rv2611c acyltransferase   0.31852
Rv1323 acetyl-CoA acetyltransferase fadA4   0.31786
Rv1312 conserved secreted protein   0.3177
Rv0660c conserved hypothetical protein   0.31765
Rv2736c regulatory protein recX   0.31699
Rv3793 membrane indolylacetylinositol arabinosyltransferase embC   0.31616
Rv2102 conserved hypothetical protein   0.31571
Rv0958 magnesium chelatase   0.3153
Rv0587 hypothetical membrane protein yrbE2A   0.3143
Rv1699 CTP synthase pyrG   0.3133
Rv1545 hypothetical protein   0.31321
Rv3244c lipoprotein lpqB   0.31291
Rv2720 repressor lexA   0.31246
Rv3807c conserved membrane protein   0.31209
Rv1700 conserved hypothetical protein   0.31206
Rv2218 lipoate biosynthesis protein A lipA   0.31178
Rv3409c cholesterol oxidase precursor choD   0.31167
Rv3692 methanol dehydrogenase transcriptional regulator moxR2   0.31122
Rv2613c conserved hypothetical protein   0.31046
Rv1666c cytochrome P450 139 cyp139   0.31032
Rv0314c conserved membrane protein   0.3097
Rv1474c transcriptional regulator   0.3096
Rv0127 conserved hypothetical protein   0.30865
Rv0525 conserved hypothetical protein   0.30809
Rv3256c conserved hypothetical protein   0.30785
Rv2670c conserved hypothetical protein   0.30651
Rv2576c conserved membrane protein   0.30644
Rv0934 periplasmic phosphate-binding lipoprotein pstS1   0.30629
Rv2402 conserved hypothetical protein   0.30499
Rv2062c cobalamin biosynthesis protein cobN   0.30479
Rv0005 DNA gyrase subunit B gyrB   0.30445
Rv1156 conserved hypothetical protein   0.30417
Rv1701 integrase   0.3038
Rv0495c conserved hypothetical protein   0.3038
Rv3028c electron transfer flavoprotein alpha subunit fixB   0.30356
Rv0954 conserved membrane protein   0.30336
Rv1326c 1,4-alpha-glucan branching enzyme glgB   0.30333
Rv0613c hypothetical protein   0.3029
Rv1880c cytochrome P450 140 cyp140   0.30218
Rv0172 MCE-family protein mce1D   0.30211
Rv3285 bifunctional acetyl-/propionyl-coenzyme A carboxylase alpha chain accA3   0.30207
Rv3031 conserved hypothetical protein   0.30103
Rv1604 inositol-monophosphatase impA   0.30083
Rv0424c hypothetical protein   0.30079
Rv1784 conserved hypothetical protein   0.30071
Rv3155 NADH dehydrogenase I chain K nuoK   0.30005