Correlation Catalog M. tuberculosis H37Rv: Rv2539c - shikimate kinase aroK

Click on the question marks for explanations Hide help
Distribution of gene correlation: Rv2539c vs. all genes ?
COG Categories ?

Information storage and processing

J Translation, ribosomal structure and biogenesis

K Transcription

I DNA replication, recombination and repair

Cellular Processes

D Cell division and chromosome partitioning

O Posttranslational modification, protein turnover, chaperones

M Cell envelope biogenesis, outer membrane

N Cell motility and secretion

P Inorganic transport and metabolism

T Signal transduction mechanisms

Metabolism

C Energy production and conversion

G Carbohydrate transport and metabolism

E Amino acid transport and metabolism

F Nucleotide transport and metabolism

H Coenzyme metabolism

I Lipid metabolism

Q Secondary metabolites biosynthesis, transport and catabolism

Poorly characterized

R General function predicton only

S Unknown function

X No COG assigned

Genes with negative correlation ?

 Categories Enriched ?: None

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv0566c conserved hypothetical protein   -0.45222
Rv0318c conserved membrane protein   -0.43302
Rv0344c lipoprotein lpqJ   -0.42939
Rv1918c PPE family protein   -0.41418
Rv2080 lipoprotein lppJ   -0.40622
Rv0456c enoyl-CoA hydratase echA2   -0.40214
Rv2046 lipoprotein lppI   -0.3991
Rv1500 glycosyltransferase   -0.39124
Rv3390 lipoprotein lpqD   -0.39062
Rv1444c hypothetical protein   -0.38814
Rv3796 conserved hypothetical protein   -0.38705
Rv1704c D-serine/alanine/glycine transporter protein cycA   -0.3846
Rv0518 hypothetical exported protein   -0.38228
Rv2267c conserved hypothetical protein   -0.38084
Rv1254 acyltransferase   -0.37794
Rv2914c transmembrane serine/threonine-protein kinase I pknI   -0.37312
Rv3378c hypothetical protein   -0.37272
Rv1722 carboxylase   -0.37247
Rv0168 hypothetical membrane protein yrbE1B   -0.37231
Rv0956 5-phosphoribosylglycinamide formyltransferase purN   -0.37229
Rv0033 acyl carrier protein acpA   -0.37215
Rv2290 lipoprotein lppO   -0.37134
Rv1368 lipoprotein lprF   -0.37009
Rv0888 hypothetical exported protein   -0.36775
Rv0506 membrane protein mmpS2   -0.36475
Rv0314c conserved membrane protein   -0.36284
Rv2856 nickel-transport membrane protein nicT   -0.36277
Rv1362c membrane protein   -0.35956
Rv0428c hypothetical protein   -0.35787
Rv0036c conserved hypothetical protein   -0.35778
Rv0890c transcriptional regulator, luxR-family   -0.35769
Rv3914 thioredoxin trxC   -0.35769
Rv3788 hypothetical protein   -0.35677
Rv1018c UDP-N-acetylglucosamine pyrophosphorylase glmU   -0.35609
Rv2082 conserved hypothetical protein   -0.35578
Rv0891c transcriptional regulator   -0.35575
Rv0097 oxidoreductase   -0.3529
Rv0924c divalent cation-transport membrane protein mntH   -0.35234
Rv0224c methyltransferase/methylase   -0.35199
Rv1270c lipoprotein lprA   -0.34747
Rv2882c ribosome recycling factor frr   -0.34469
Rv3676 transcriptional regulator, crp/fnr-family   -0.34354
Rv3792 conserved membrane protein   -0.34313
Rv3528c hypothetical protein   -0.34248
Rv1903 conserved membrane protein   -0.34155
Rv0565c monooxygenase   -0.34147
Rv1454c quinone reductase qor   -0.3411
Rv1618 acyl-CoA thioesterase II tesB1   -0.34075
Rv1824 conserved membrane protein   -0.34019
Rv3820c polyketide synthase associated protein papA2   -0.33922
Rv0732 preprotein translocase secY   -0.33799
Rv3224 iron-regulated short-chain dehydrogenase/reductase   -0.33657
Rv3291c transcriptional regulator, asnC-family   -0.33651
Rv0402c transmembrane transport protein mmpL1   -0.33582
Rv2268c cytochrome P450 128 cyp128   -0.33385
Rv1538c L-aparaginase ansA   -0.33306
Rv0936 phosphate-transport membrane ABC transporter pstA2   -0.33259
Rv3826 fatty-acid-CoA ligase fadD23   -0.33118
Rv1640c lysyl-tRNA synthetase 2 lysX   -0.33029
Rv0772 phosphoribosylamine-glycine ligase purD   -0.32983
Rv0165c transcriptional regulator, gntR-family   -0.32924
Rv0759c conserved hypothetical protein   -0.32758
Rv0108c hypothetical protein   -0.32667
Rv1282c oligopeptide-transport membrane protein ABC transporter oppC   -0.32637
Rv3438 conserved hypothetical protein   -0.32571
Rv3750c excisionase   -0.32537
Rv0942 hypothetical protein   -0.32523
Rv3218 conserved hypothetical protein   -0.32516
Rv2481c hypothetical protein   -0.32228
Rv0334 alpha-D-glucose-1-phosphate thymidylyltransferase rmlA   -0.32103
Rv2954c hypothetical protein   -0.31842
Rv0926c conserved hypothetical protein   -0.31803
Rv0740 conserved hypothetical protein   -0.31799
Rv2510c conserved hypothetical protein   -0.31694
Rv0166 fatty-acid-CoA ligase fadD5   -0.31645
Rv0222 enoyl-CoA hydratase echA1   -0.31637
Rv1666c cytochrome P450 139 cyp139   -0.3162
Rv1505c conserved hypothetical protein   -0.31551
Rv0208c methlytransferase   -0.31483
Rv3900c conserved alanine rich protein   -0.31368
Rv3798 transposase   -0.31221
Rv2140c conserved hypothetical protein   -0.31036
Rv0058 replicative DNA helicase dnaB   -0.31021
Rv0338c iron-sulfur-binding reductase   -0.30933
Rv0504c conserved hypothetical protein   -0.30858
Rv0991c conserved serine rich protein   -0.3082
Rv2301 cutinase cut2   -0.30808
Rv0798c 29 kda antigen cfp29   -0.30728
Rv0001 chromosomal replication initiator protein dnaA   -0.30691
Rv2808 hypothetical protein   -0.30673
Rv2302 conserved hypothetical protein   -0.30631
Rv3494c MCE-family protein mce4F   -0.30502
Rv2066 bifunctional cobI-cobJ fusion protein   -0.30453
Rv0032 8-amino-7-oxononanoate synthase bioF2   -0.30305
Rv2408 PE family protein   -0.3028
Rv0961 membrane protein   -0.30257
Rv1624c conserved membrane protein   -0.3025
Rv0128 conserved membrane protein   -0.30229
Rv1242 conserved hypothetical protein   -0.30185
Rv0728c D-3-phosphoglycerate dehydrogenase serA2   -0.30148
Rv0696 membrane sugar transferase   -0.30128
Rv0118c oxalyl-CoA decarboxylase oxcA   -0.30119
Rv2054 conserved hypothetical protein   -0.30061

Genes with positive correlation ?

 Categories Enriched ?: None

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv1583c phiRv1 phage protein   0.50565
Rv2540c chorismate synthase aroF   0.48785
Rv1599 histidinol dehydrogenase hisD   0.4787
Rv0015c transmembrane serine/threonine-protein kinase A pknA   0.4749
Rv1243c PE-PGRS family protein   0.46982
Rv3421c conserved hypothetical protein   0.46359
Rv0615 membrane protein   0.44201
Rv2471 alpha-glucosidase aglA   0.44107
Rv1576c phiRv1 phage protein   0.4402
Rv3535c acetaldehyde dehydrogenase   0.4372
Rv0617 conserved hypothetical protein   0.43432
Rv1005c para-aminobenzoate synthase component I pabD   0.42905
Rv1603 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase hisA   0.42705
Rv1595 L-aspartate oxidase nadB   0.42562
Rv2161c conserved hypothetical protein   0.42367
Rv1415 riboflavin biosynthesis protein ribA2   0.42277
Rv3411c inosine-5-monophosphate dehydrogenase guaB2   0.42145
Rv1600 histidinol-phosphate aminotransferase hisC1   0.41746
Rv2373c chaperone protein dnaJ2   0.4161
Rv2103c conserved hypothetical protein   0.41565
Rv3385c conserved hypothetical protein   0.41535
Rv1601 imidazole glycerol-phosphate dehydratase hisB   0.41184
Rv2009 conserved hypothetical protein   0.41113
Rv0973c acetyl-/propionyl-CoA carboxylase alpha subunit accA2   0.41011
Rv0301 conserved hypothetical protein   0.40649
Rv2925c ribonuclease III rnc   0.40415
Rv3422c conserved hypothetical protein   0.39996
Rv1605 cyclase hisF   0.39951
Rv2749 conserved hypothetical protein   0.39399
Rv3595c PE-PGRS family protein   0.39343
Rv3093c oxidoreductase   0.39332
Rv2181 conserved membrane protein   0.3929
Rv3345c PE-PGRS family protein   0.39204
Rv2933 phenolpthiocerol synthesis type-I polyketide synthase ppsC   0.38935
Rv1797 conserved hypothetical protein   0.3886
Rv3857c membrane protein   0.38859
Rv2839c translation initiation factor IF-2 infB   0.38848
Rv3743c cation transporter P-type ATPase ctpJ   0.38781
Rv2503c succinyl-CoA:3-ketoacid-coenzyme A transferase beta subunit scoB   0.38745
Rv1818c PE-PGRS family protein   0.38572
Rv1127c pyruvate, phosphate dikinase ppdK   0.38422
Rv1789 PPE family protein   0.38168
Rv2374c heat shock protein transcriptional repressor hrcA   0.38166
Rv1091 PE-PGRS family protein   0.38116
Rv2497c pyruvate dehydrogenase E1 component alpha subunit pdhA   0.37873
Rv1671 membrane protein   0.37831
Rv2923c conserved hypothetical protein   0.37703
Rv2589 4-aminobutyrate aminotransferase gabT   0.37475
Rv1495 conserved hypothetical protein   0.37429
Rv3065 multidrugs transport membrane protein mmr   0.37401
Rv3167c transcriptional regulator, tetR-family   0.37297
Rv0513 conserved membrane protein   0.37163
Rv3627c conserved hypothetical protein   0.37161
Rv0875c hypothetical exported protein   0.37141
Rv3563 acyl-CoA dehydrogenase fadE32   0.36937
Rv2126c PE-PGRS family protein   0.3678
Rv2825c conserved hypothetical protein   0.36762
Rv2417c conserved hypothetical protein   0.36729
Rv1593c conserved hypothetical protein   0.36618
Rv2117 conserved hypothetical protein   0.36217
Rv2583c GTP pyrophosphokinase relA   0.36215
Rv2697c deoxyuridine 5-triphosphate nucleotidohydrolase dut   0.36184
Rv1381 dihydroorotase pyrC   0.36168
Rv2919c nitrogen regulatory protein P-II glnB   0.36153
Rv0275c transcriptional regulator, tetR-family   0.36135
Rv1845c conserved membrane protein   0.3593
Rv2887 transcriptional regulator   0.35922
Rv1389 guanylate kinase gmk   0.35799
Rv1301 conserved hypothetical protein   0.35728
Rv0998 conserved hypothetical protein   0.35682
Rv2131c monophosphatase cysQ   0.35649
Rv3429 PPE family protein   0.35566
Rv2345 conserved membrane protein   0.35552
Rv2827c hypothetical protein   0.35499
Rv1627c nonspecific lipid-transfer protein   0.35481
Rv2134c conserved hypothetical protein   0.35481
Rv1577c phiRv1 phage protein   0.35296
Rv3423c alanine racemase alr   0.35278
Rv0809 phosphoribosylformylglycinamidine cyclo-ligase purM   0.35186
Rv1597 hypothetical protein   0.35134
Rv2826c hypothetical protein   0.35076
Rv2665 hypothetical arginine rich protein   0.35057
Rv1820 acetolactate synthase ilvG   0.34957
Rv0327c cytochrome P450 135A1 cyp135A1   0.34949
Rv2853 PE-PGRS family protein   0.34816
Rv3003c acetolactate synthase large subunit ilvB1   0.34766
Rv3507 PE-PGRS family protein   0.34746
Rv3917c chromosome partitioning protein parB   0.34741
Rv0818 transcriptional regulator   0.34734
Rv3653 PE-PGRS family protein   0.34704
Rv1939 oxidoreductase   0.34675
Rv0627 conserved hypothetical protein   0.34656
Rv2125 conserved hypothetical protein   0.34448
Rv0486 mannosyltransferase   0.34296
Rv1007c methionyl-tRNA synthetase metS   0.34273
Rv2533c N utilization substance protein B nusB   0.34207
Rv2921c cell division protein ftsY   0.34171
Rv3573c acyl-CoA dehydrogenase fadE34   0.34125
Rv2559c conserved alanine, leucine valine rich protein   0.34115
Rv0578c PE-PGRS family protein   0.3405
Rv1655 acetylornithine aminotransferase argD   0.33976
Rv2327 conserved hypothetical protein   0.33886
Rv0283 conserved membrane protein   0.33851
Rv3919c glucose-inhibited division protein B gid   0.33767
Rv1396c PE-PGRS family protein   0.33637
Rv0477 conserved secreted protein   0.33568
Rv1003 conserved hypothetical protein   0.33467
Rv2249c glycerol-3-phosphate dehydrogenase glpD1   0.33458
Rv1407 SUN protein   0.33404
Rv3537 dehydrogenase   0.33336
Rv2974c conserved alanine rich protein   0.33147
Rv1602 amidotransferase hisH   0.33063
Rv1225c conserved hypothetical protein   0.33062
Rv2365c conserved hypothetical protein   0.33053
Rv2653c phiRv2 phage protein   0.33033
Rv2291 thiosulfate sulfurtransferase sseB   0.32941
Rv0859 acyl-CoA thiolase fadA   0.32881
Rv1087 PE-PGRS family protein   0.32866
Rv2160c conserved hypothetical protein   0.32823
Rv1628c conserved hypothetical protein   0.32779
Rv2793c tRNA pseudouridine synthase B truB   0.32747
Rv2688c antibiotic-transport ATP-binding protein ABC transporter   0.32606
Rv3741c oxidoreductase   0.32505
Rv2010 conserved hypothetical protein   0.32465
Rv3859c ferredoxin-dependent glutamate synthase large subunit gltB   0.32405
Rv2371 PE-PGRS family protein   0.32378
Rv1775 conserved hypothetical protein   0.3237
Rv3201c ATP-dependent DNA helicase   0.32331
Rv2851c conserved hypothetical protein   0.32321
Rv2444c ribonuclease E rne   0.32282
Rv1635c conserved membrane protein   0.32263
Rv3212 conserved alanine and valine rich protein   0.32165
Rv1405c methyltransferase   0.32096
Rv1209 conserved hypothetical protein   0.32089
Rv2304c hypothetical protein   0.31988
Rv2159c conserved hypothetical protein   0.31975
Rv0711 arylsulfatase atsA   0.31902
Rv2704 conserved hypothetical protein   0.31848
Rv2535c cytoplasmic peptidase pepQ   0.3172
Rv3079c conserved hypothetical protein   0.31697
Rv3182 conserved hypothetical protein   0.31602
Rv3905c Esat-6 like protein esxF   0.31581
Rv2829c conserved hypothetical protein   0.31561
Rv3871 conserved hypothetical protein   0.31557
Rv2726c diaminopimelate epimerase dapF   0.31516
Rv0860 fatty-acid oxidation protein fadB   0.31504
Rv3504 acyl-CoA dehydrogenase fadE26   0.31459
Rv0813c conserved hypothetical protein   0.31449
Rv3516 enoyl-CoA hydratase echA19   0.3142
Rv3546 acetyl-CoA acetyltransferase fadA5   0.31378
Rv1929c conserved hypothetical protein   0.31292
Rv3270 metal cation transporting P-type ATPase ctpC   0.31291
Rv3590c PE-PGRS family protein   0.31085
Rv2811 conserved hypothetical protein   0.3101
Rv2551c conserved hypothetical protein   0.30922
Rv1391 DNA/pantothenate metabolism flavoprotein dfp   0.30826
Rv2498c citrate (pro-3s)-lyase beta subunit citE   0.30781
Rv2651c phiRv2 phage protease   0.30768
Rv3183 transcriptional regulator   0.30698
Rv3384c conserved hypothetical protein   0.30558
Rv1539 lipoprotein signal peptidase lspA   0.30468
Rv0383c conserved secreted protein   0.30436
Rv3663c dipeptide-transport ATP-binding protein ABC transporter dppD   0.30389
Rv1585c phiRv1 phage protein   0.30326
Rv1487 conserved membrane protein   0.30296
Rv3367 PE-PGRS family protein   0.30211
Rv1211 conserved hypothetical protein   0.302
Rv3060c transcriptional regulator, gntR-family   0.30109