Correlation Catalog M. tuberculosis H37Rv: Rv2446c - conserved membrane protein

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Distribution of gene correlation: Rv2446c vs. all genes ?
COG Categories ?

Information storage and processing

J Translation, ribosomal structure and biogenesis

K Transcription

I DNA replication, recombination and repair

Cellular Processes

D Cell division and chromosome partitioning

O Posttranslational modification, protein turnover, chaperones

M Cell envelope biogenesis, outer membrane

N Cell motility and secretion

P Inorganic transport and metabolism

T Signal transduction mechanisms

Metabolism

C Energy production and conversion

G Carbohydrate transport and metabolism

E Amino acid transport and metabolism

F Nucleotide transport and metabolism

H Coenzyme metabolism

I Lipid metabolism

Q Secondary metabolites biosynthesis, transport and catabolism

Poorly characterized

R General function predicton only

S Unknown function

X No COG assigned

Genes with negative correlation ?

 Categories Enriched ?: P

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv3287c anti-sigma factor rsbW   -0.44547
Rv1393c monooxygenase   -0.44286
Rv1868 conserved hypothetical protein   -0.43418
Rv3809c UDP-galactopyranose mutase glf   -0.43415
Rv1777 cytochrome P450 144 cyp144   -0.43339
Rv1029 potassium-transporting ATPase A chain kdpA   -0.42108
Rv0064 conserved membrane protein   -0.40777
Rv1031 potassium-transporting ATPase C chain kdpC   -0.40474
Rv2115c ATPase   -0.4032
Rv1620c transmembrane ATP-binding protein ABC transporter cydC   -0.40231
Rv0837c hypothetical protein   -0.39953
Rv0981 mycobacterial persistence regulator mprA   -0.39625
Rv2659c phiRv2 phage integrase   -0.39406
Rv3427c transposase   -0.39336
Rv0620 galactokinase galK   -0.38968
Rv1893 conserved hypothetical protein   -0.38605
Rv1284 conserved hypothetical protein   -0.38432
Rv1955 hypothetical protein   -0.38414
Rv2557 conserved hypothetical protein   -0.3838
Rv2709 conserved membrane protein   -0.38269
Rv2359 ferric uptake regulation protein furB   -0.38182
Rv0873 acyl-CoA dehydrogenase fadE10   -0.37909
Rv1743 transmembrane serine/threonine-protein kinase E pknE   -0.37743
Rv1575 phiRv1 phage protein   -0.37722
Rv2577 conserved hypothetical protein   -0.37619
Rv0977 PE-PGRS family protein   -0.37335
Rv3714c conserved hypothetical protein   -0.37279
Rv2683 conserved hypothetical protein   -0.37266
Rv1394c cytochrome P450 132 cyp132   -0.3691
Rv0937c conserved hypothetical protein   -0.36872
Rv1414 conserved hypothetical protein   -0.36481
Rv1574 phiRv1 phage protein   -0.36367
Rv0976c conserved hypothetical protein   -0.36365
Rv0812 amino acid aminotransferase   -0.36342
Rv2663 hypothetical protein   -0.36295
Rv1039c PPE family protein   -0.36251
Rv3359 oxidoreductase   -0.36188
Rv1239c magnesium and cobalt transport transmembrane protein corA   -0.36126
Rv3288c hypothetical protein usfY   -0.36075
Rv0233 ribonucleoside-diphosphate reductase beta chain nrdB   -0.35998
Rv1582c phiRv1 phage protein   -0.35947
Rv1419 hypothetical protein   -0.35932
Rv1020 transcription-repair coupling factor mfd   -0.3578
Rv3749c conserved hypothetical protein   -0.35455
Rv1910c hypothetical exported protein   -0.3544
Rv1187 pyrroline-5-carboxylate dehydrogenase rocA   -0.3544
Rv1761c hypothetical exported protein   -0.3538
Rv3333c hypothetical proline rich protein   -0.35343
Rv3637 transposase   -0.3531
Rv1990c transcriptional regulator   -0.35265
Rv1752 conserved hypothetical protein   -0.35184
Rv1646 PE family protein   -0.35002
Rv1433 hypothetical exported protein   -0.34993
Rv1991c conserved hypothetical protein   -0.3471
Rv2515c conserved hypothetical protein   -0.34667
Rv0836c hypothetical protein   -0.34655
Rv1027c transcriptional regulator kdpE   -0.34628
Rv3290c L-lysine-epsilon aminotransferase lat   -0.34591
Rv0277c conserved hypothetical protein   -0.3443
Rv0027 hypothetical protein   -0.34416
Rv2089c dipeptidase pepE   -0.34329
Rv1995 hypothetical protein   -0.34287
Rv0304c PPE family protein   -0.34282
Rv3128c conserved hypothetical protein   -0.34262
Rv0399c lipoprotein lpqK   -0.34025
Rv3327 transposase   -0.33912
Rv3527 hypothetical protein   -0.33748
Rv3760 conserved membrane protein   -0.33723
Rv1829 conserved hypothetical protein   -0.33703
Rv3241c conserved hypothetical protein   -0.33544
Rv3699 conserved hypothetical protein   -0.33538
Rv1499 hypothetical protein   -0.3352
Rv2369c hypothetical protein   -0.33439
Rv2322c ornithine aminotransferase rocD1   -0.33397
Rv0261c membrane nitrite extrusion protein narK3   -0.33367
Rv2688c antibiotic-transport ATP-binding protein ABC transporter   -0.33319
Rv1724c hypothetical protein   -0.33312
Rv1926c immunogenic protein mpt63   -0.33307
Rv1989c hypothetical protein   -0.33158
Rv0262c aminoglycoside 2-N-acetyltransferase aac   -0.33102
Rv2016 hypothetical protein   -0.33088
Rv0621 membrane protein   -0.32954
Rv1291c conserved secreted protein   -0.32899
Rv2042c conserved hypothetical protein   -0.32894
Rv0671 lipoprotein lpqP   -0.32808
Rv1270c lipoprotein lprA   -0.32654
Rv0355c PPE family protein   -0.3265
Rv0274 conserved hypothetical protein   -0.32642
Rv0267 membrane nitrite extrusion protein narU   -0.32638
Rv0076c membrane protein   -0.32622
Rv1139c conserved membrane protein   -0.32494
Rv2227 conserved hypothetical protein   -0.32486
Rv1075c conserved exported protein   -0.32472
Rv1489c   -0.3243
Rv3615c conserved hypothetical protein   -0.32423
Rv2029c phosphofructokinase pfkB   -0.32321
Rv2034 arsR-type repressor protein   -0.3203
Rv1975 conserved hypothetical protein   -0.31951
Rv3109 molybdenum cofactor biosynthesis protein A moaA1   -0.31796
Rv1978 conserved hypothetical protein   -0.31775
Rv0874c conserved hypothetical protein   -0.31679
Rv1716 conserved hypothetical protein   -0.31618
Rv0311 hypothetical protein   -0.31598
Rv1888c transmembrane protein   -0.31558
Rv1909c ferric uptake regulation protein furA   -0.31542
Rv0806c UDP-glucose-4-epimerase cpsY   -0.31525
Rv1760 conserved hypothetical protein   -0.31487
Rv2035 conserved hypothetical protein   -0.31375
Rv1670 conserved hypothetical protein   -0.31363
Rv2169c conserved membrane protein   -0.31291
Rv1404 transcriptional regulator   -0.31266
Rv0116c conserved membrane protein   -0.31205
Rv0407 F420-dependent glucose-6-phosphate dehydrogenase fgd1   -0.31104
Rv3819 hypothetical protein   -0.31098
Rv1997 metal cation transporting P-type ATPase ctpF   -0.31084
Rv0150c conserved hypothetical protein   -0.31055
Rv0751c 3-hydroxyisobutyrate dehydrogenase mmsB   -0.31034
Rv0441c hypothetical protein   -0.30917
Rv0779c conserved membrane protein   -0.30909
Rv2170 conserved hypothetical protein   -0.30846
Rv0259c conserved hypothetical protein   -0.30817
Rv3349c transposase   -0.30801
Rv1675c transcriptional regulator   -0.30762
Rv2541 hypothetical alanine rich protein   -0.30695
Rv0426c transmembrane protein   -0.3066
Rv2817c conserved hypothetical protein   -0.3063
Rv2804c hypothetical protein   -0.30464
Rv2473 alanine and proline rich membrane protein   -0.30442
Rv3526 oxidoreductase   -0.30372
Rv3746c PE family protein   -0.30354
Rv0278c PE-PGRS family protein   -0.30212
Rv2491 conserved hypothetical protein   -0.30198
Rv3845 hypothetical protein   -0.30179
Rv1672c conserved membrane transport protein   -0.30175
Rv1403c methyltransferase   -0.3015
Rv3087 conserved hypothetical protein   -0.30142
Rv2059 conserved hypothetical protein   -0.30107
Rv1581c phiRv1 phage protein   -0.30084
Rv1805c hypothetical protein   -0.30048
Rv0052 conserved hypothetical protein   -0.30024
Rv2504c succinyl-CoA:3-ketoacid-coenzyme A transferase alpha subunit scoA   -0.30016
Rv0816c thioredoxin thiX   -0.30014

Genes with positive correlation ?

 Categories Enriched ?: J

Gene ?DescriptionLinks ?COG ?Correlation ?
Rv1452c PE-PGRS family protein   0.60749
Rv2490c PE-PGRS family protein   0.57013
Rv0532 PE-PGRS family protein   0.54929
Rv2862c conserved hypothetical protein   0.54207
Rv2591 PE-PGRS family protein   0.53564
Rv3508 PE-PGRS family protein   0.5268
Rv3678c conserved hypothetical protein   0.51272
Rv2836c DNA-damage-inducible protein F dinF   0.50866
Rv1178 aminotransferase   0.50846
Rv3920c hypothetical protein   0.50054
Rv0954 conserved membrane protein   0.49669
Rv0200 conserved membrane protein   0.49417
Rv3028c electron transfer flavoprotein alpha subunit fixB   0.48775
Rv2594c crossover junction endodeoxyribonuclease ruvC   0.48487
Rv3512 PE-PGRS family protein   0.47973
Rv2126c PE-PGRS family protein   0.47757
Rv3579c tRNA/rRNA methyltransferase   0.46075
Rv1209 conserved hypothetical protein   0.46001
Rv1484 NADH-dependent enoyl-[acyl-carrier-protein] reductase inhA   0.45692
Rv1613 tryptophan synthase, alpha subunit trpA   0.45529
Rv1590 conserved hypothetical protein   0.45165
Rv1133c 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase metE   0.45155
Rv0460 conserved hydrophobic protein   0.4482
Rv0668 DNA-directed RNA polymerase beta chain rpoC   0.44772
Rv3726 dehydrogenase   0.44292
Rv3277 conserved membrane protein   0.43995
Rv1837c malate synthase G glcB   0.43735
Rv2468c conserved hypothetical protein   0.43609
Rv1380 aspartate carbamoyltransferase pyrB   0.43224
Rv2940c multifunctional mycocerosic acid synthase membrane-associated mas   0.42902
Rv1650 phenylalanyl-tRNA synthetase beta chain pheT   0.42835
Rv0707 30S ribosomal protein S3 rpsC   0.41956
Rv0734 methionine aminopeptidase mapA   0.4134
Rv1842c conserved membrane protein   0.41326
Rv1751 oxidoreductase   0.41089
Rv0667 DNA-directed RNA polymerase beta chain rpoB   0.41082
Rv2883c uridylate kinase pyrH   0.41061
Rv0434 conserved hypothetical protein   0.40836
Rv1595 L-aspartate oxidase nadB   0.40703
Rv3220c two component system sensor kinase   0.40304
Rv3221c biotinylated protein   0.40095
Rv0708 50S ribosomal protein L16 rplP   0.40079
Rv2065 precorrin-8x methylmutase cobH   0.40027
Rv3748 conserved hypothetical protein   0.40018
Rv2732c conserved membrane protein   0.39862
Rv3458c 30S ribosomal protein S4 rpsD   0.39593
Rv1611 indole-3-glycerol phosphate synthase trpC   0.39575
Rv1655 acetylornithine aminotransferase argD   0.39439
Rv2048c hypothetical protein   0.39352
Rv3025c cysteine desulfurase iscS   0.39329
Rv3580c cysteinyl-tRNA synthetase 1 cysS1   0.39009
Rv0721 30S ribosomal protein S5 rpsE   0.38891
Rv0723 50S ribosomal protein L15 rplO   0.38831
Rv2782c zinc protease pepR   0.38812
Rv1386 PE family protein   0.38678
Rv2778c conserved hypothetical protein   0.38559
Rv2772c conserved membrane protein   0.38511
Rv3805c conserved membrane protein   0.38297
Rv3794 membrane indolylacetylinositol arabinosyltransferase embA   0.38282
Rv1340 ribonuclease rphA   0.3821
Rv0720 50S ribosomal protein L18 rplR   0.38172
Rv1091 PE-PGRS family protein   0.38167
Rv0664 hypothetical protein   0.38131
Rv0308 conserved membrane protein   0.38077
Rv1312 conserved secreted protein   0.38011
Rv2888c amidase amiC   0.38
Rv1597 hypothetical protein   0.37866
Rv0706 50S ribosomal protein L22 rplV   0.37819
Rv1311 ATP synthase epsilon chain atpC   0.37751
Rv1836c conserved hypothetical protein   0.37724
Rv3264c D-alpha-D-mannose-1-phosphate guanylyltransferase manB   0.37677
Rv0705 30S ribosomal protein S19 rpsS   0.37657
Rv2768c PPE family protein   0.37342
Rv0722 50S ribosomal protein L30 rpmD   0.37322
Rv3271c conserved membrane protein   0.37235
Rv1713 GTP-binding protein engA   0.3706
Rv2573 conserved hypothetical protein   0.37043
Rv3222c conserved hypothetical protein   0.37039
Rv3456c 50S ribosomal protein L17 rplQ   0.36971
Rv1387 PPE family protein   0.3689
Rv3804c secreted fibronectin-binding protein antigen fbpA   0.36802
Rv0545c low affinity inorganic phosphate transporter membrane protein pitA   0.36757
Rv1591 transmembrane protein   0.36573
Rv3248c adenosylhomocysteinase sahH   0.36528
Rv1436 glyceraldehyde 3-phosphate dehydrogenase gap   0.36507
Rv1196 PPE family protein   0.36454
Rv2802c hypothetical alanine and arginine rich protein   0.36236
Rv2184c conserved hypothetical protein   0.36176
Rv2238c peroxiredoxin ahpE   0.36167
Rv0613c hypothetical protein   0.36082
Rv2736c regulatory protein recX   0.36081
Rv3233c conserved hypothetical protein   0.36013
Rv2572c aspartyl-tRNA synthetase aspS   0.35996
Rv0718 30S ribosomal protein S8 rpsH   0.35882
Rv0288 low molecular weight protein antigen 7 esxH   0.35859
Rv0636 conserved hypothetical protein   0.35818
Rv3276c phosphoribosylaminoimidazole carboxylase ATPase subunit purK   0.35767
Rv0562 polyprenyl-diphosphate synthase grcC1   0.35689
Rv3653 PE-PGRS family protein   0.35621
Rv0684 elongation factor G fusA1   0.35557
Rv3265c dTDP-rha:a-D-glcnac-diphosphoryl polyprenol, a-3-L-rhamnosyl transferase wbbL1   0.3551
Rv3020c Esat-6 like protein esxS   0.35482
Rv2197c conserved membrane protein   0.35467
Rv2156c phospho-N-acetylmuramoyl-pentappeptidetransferase murX   0.35464
Rv0248c succinate dehydrogenase iron-sulfur subunit   0.35455
Rv0554 non-haem peroxidase bpoC   0.35412
Rv3411c inosine-5-monophosphate dehydrogenase guaB2   0.35341
Rv3217c conserved membrane protein   0.35334
Rv3821 conserved membrane protein   0.35256
Rv3921c conserved membrane protein   0.35225
Rv0957 bifunctional purine biosynthesis protein purH   0.35142
Rv3799c propionyl-CoA carboxylase beta chain 4 accD4   0.35103
Rv3922c hemolysin   0.3509
Rv3275c phosphoribosylaminoimidazole carboxylase catalytic subunit purE   0.35079
Rv0285 PE family protein   0.35063
Rv1480 conserved hypothetical protein   0.34953
Rv2462c trigger factor protein tig   0.34937
Rv2216 conserved hypothetical protein   0.34919
Rv0637 conserved hypothetical protein   0.3491
Rv1631 dephospho-CoA kinase coaE   0.34843
Rv2783c bifunctional polyribonucleotide nucleotidyltransferase gpsI   0.34814
Rv0641 50S ribosomal protein L1 rplA   0.34792
Rv1641 initiation factor IF-3 infC   0.34707
Rv1328 glycogen phosphorylase glgP   0.34676
Rv1307 ATP synthase delta chain atpH   0.34376
Rv2762c conserved hypothetical protein   0.34345
Rv3465 dTDP-4-dehydrorhamnose 3,5-epimerase rmlC   0.3428
Rv1324 thioredoxin   0.34272
Rv3234c conserved hypothetical protein   0.34167
Rv0760c conserved hypothetical protein   0.34163
Rv1173 F420 biosynthesis protein fbiC   0.34116
Rv0206c transmembrane transport protein mmpL3   0.34113
Rv3004 low molecular weight protein antigen 6 cfp6   0.3408
Rv0287 esat-6 like protein esxG   0.34074
Rv1828 conserved hypothetical protein   0.34064
Rv2996c D-3-phosphoglycerate dehydrogenase serA1   0.33986
Rv0702 50S ribosomal protein L4 rplD   0.33967
Rv3031 conserved hypothetical protein   0.33966
Rv2845c prolyl-tRNA synthetase proS   0.3394
Rv2831 enoyl-CoA hydratase echA16   0.33898
Rv3442c 30S ribosomal protein S9 rpsI   0.33806
Rv2982c glycerol-3-phosphate dehydrogenase gpdA2   0.33769
Rv1226c transmembrane protein   0.33765
Rv3457c DNA-directed RNA polymerase alpha chain rpoA   0.3376
Rv3631 transferase   0.33743
Rv0709 50S ribosomal protein L29 rpmC   0.33731
Rv1309 ATP synthase gamma chain atpG   0.33725
Rv2881c membrane phosphatidate cytidylyltransferase cdsA   0.33644
Rv0652 50S ribosomal protein L7/L12 rplL   0.33563
Rv0719 50S ribosomal protein L6 rplF   0.33452
Rv2552c shikimate 5-dehydrogenase aroE   0.33432
Rv3478 PPE family protein   0.33412
Rv3708c aspartate-semialdehyde dehydrogenase asd   0.3337
Rv0083 oxidoreductase   0.33321
Rv1610 conserved membrane protein   0.33156
Rv3200c transmembrane cation transporter   0.33123
Rv3001c ketol-acid reductoisomerase ilvC   0.33107
Rv2463 esterase/lipase lipP   0.33099
Rv0461 transmembrane protein   0.3303
Rv0528 conserved membrane protein   0.32999
Rv0933 phosphate-transport ATP-binding protein ABC transporter pstB   0.32989
Rv2196 ubiquinol-cytochrome C reductase qcrB cytochrome B subunit   0.32984
Rv0710 30S ribosomal protein S17 rpsQ   0.32977
Rv2858c aldehyde dehydrogenase aldC   0.32953
Rv0513 conserved membrane protein   0.32924
Rv2696c conserved alanine, glycine and valine rich protein   0.32863
Rv0685 iron-regulated elongation factor tu tuf   0.32863
Rv3780 conserved hypothetical protein   0.32855
Rv2144c transmembrane protein   0.32803
Rv2587c protein-export membrane protein secD   0.32775
Rv2837c conserved hypothetical protein   0.32697
Rv2956 conserved hypothetical protein   0.3267
Rv2528c restriction system protein mrr   0.32617
Rv2936 daunorubicin-dim-transport ATP-binding protein ABC transporter drrA   0.32549
Rv3247c thymidylate kinase tmk   0.32536
Rv3216 acetyltransferase   0.32489
Rv1006 hypothetical protein   0.32429
Rv2039c sugar-transport membrane protein ABC transporter   0.32404
Rv3015c conserved hypothetical protein   0.32373
Rv0463 conserved membrane protein   0.32326
Rv1860 alanine and proline rich secreted protein apa   0.32324
Rv1078 proline-rich antigen pra   0.32317
Rv2843 conserved alanine rich membrane protein   0.32294
Rv3104c conserved membrane protein   0.3228
Rv0337c aspartate aminotransferase aspC   0.32279
Rv3590c PE-PGRS family protein   0.32215
Rv0682 30S ribosomal protein S12 rpsL   0.32213
Rv0704 50S ribosomal protein L2 rplB   0.32167
Rv0952 succinyl-CoA synthetase alpha chain sucD   0.32113
Rv2477c macrolide-transport ATP-binding protein ABC transporter   0.3204
Rv3793 membrane indolylacetylinositol arabinosyltransferase embC   0.32022
Rv2509 short-chain type dehydrogenase/reductase   0.31871
Rv3030 conserved hypothetical protein   0.31835
Rv2195 Rieske iron-sulfur protein qcrA   0.31793
Rv3261 F420 biosynthesis protein fbiA   0.31769
Rv1689 tyrosyl-tRNA synthase tyrS   0.3172
Rv1305 ATP synthase C chain atpE   0.31682
Rv3778c aminotransferase   0.3168
Rv0578c PE-PGRS family protein   0.31657
Rv2792c resolvase   0.31588
Rv1626 two component system transcriptional regulator   0.31547
Rv1297 transcription termination factor rho   0.31516
Rv0683 30S ribosomal protein S7 rpsG   0.31499
Rv3106 NADPH:adrenodoxin oxidoreductase fprA   0.31479
Rv2402 conserved hypothetical protein   0.31453
Rv3417c 60 kda chaperonin 1 groEL1   0.31411
Rv2702 polyphosphate glucokinase ppgK   0.31388
Rv3258c conserved hypothetical protein   0.31378
Rv3255c mannose-6-phosphate isomerase manA   0.31354
Rv0660c conserved hypothetical protein   0.31302
Rv2190c conserved hypothetical protein   0.31295
Rv0220 esterase lipC   0.31192
Rv2739c alanine rich transferase   0.31142
Rv0237 lipoprotein lpqI   0.31101
Rv3418c 10 kda chaperonin groES   0.31056
Rv2604c conserved hypothetical protein   0.31045
Rv2908c conserved hypothetical protein   0.31016
Rv3629c conserved membrane protein   0.31011
Rv2844 conserved alanine rich protein   0.31009
Rv1310 ATP synthase beta chain atpD   0.30973
Rv2700 conserved secreted protein   0.30937
Rv3364c conserved hypothetical protein   0.30825
Rv1596 nicotinate-nucleotide pyrophosphatase nadC   0.30808
Rv2838c ribosome-binding factor A rbfA   0.30796
Rv0701 50S ribosomal protein L3 rplC   0.30778
Rv1295 threonine synthase thrC   0.30775
Rv3002c acetolactate synthase small subunit ilvN   0.30757
Rv0832 PE-PGRS family protein   0.30753
Rv2430c PPE family protein   0.3072
Rv3298c esterase lipoprotein lpqC   0.30716
Rv2146c conserved membrane protein   0.30701
Rv3807c conserved membrane protein   0.30598
Rv0462 dihydrolipoamide dehydrogenase lpd   0.30574
Rv0290 conserved membrane protein   0.30563
Rv2102 conserved hypothetical protein   0.30532
Rv3671c membrane-associated serine protease   0.3049
Rv0761c zinc-type alcohol dehydrogenase NAD dependent adhB   0.30387
Rv3212 conserved alanine and valine rich protein   0.3037
Rv2798c conserved hypothetical protein   0.30303
Rv3828c resolvase   0.30291
Rv1612 tryptophan synthase, beta subunit trpB   0.30248
Rv1306 ATP synthase B chain atpF   0.30239
Rv3210c conserved hypothetical protein   0.30239
Rv2904c 50S ribosomal protein L19 rplS   0.30129
Rv1336 cysteine synthase B cysM   0.30058
Rv1449c transketolase tkt   0.30051
Rv2890c 30S ribosomal protein S2 rpsB   0.30041
Rv3803c secreted fibronectin-binding protein antigen protein fbpD   0.30022